酒精与几种常见有机磷农药联合毒性的研究

法医学杂志 ›› 1987, Vol. 0 ›› Issue (1): 5-8.

酒精与几种常见有机磷农药联合毒性的研究

朱广友;颜零;卜俊;邓丽平;

司法部司法鉴定科学技术究所法化学研究室,司法部司法鉴定科学技术究所法化学研究室,司法部司法鉴定科学技术究所法化学研究室,司法部司法鉴定科学技术究所法化学研究室,

发布日期:1987-02-25 出版日期:1987-02-28

Effect of Interaction of Alcohol Combined with Commonly Used Organohposphates Pesticides.

ZHU GUANGYOU, YAN LING,BU JUN, DENG LIPING

Online:1987-02-25 Published:1987-02-28

摘要/Abstract

摘要： <正> 对于酒精或有机磷农药中毒的法医学鉴定,是以酒精或有机磷农药单味药物的口服致死量或血液致死浓度为主要依据的,但是,在司法实践中往往见到将有机磷农药掺入酒类饮料中自杀或他杀者.对于这一类案例的鉴定,由于酒精和有机磷农药的联合作用,可能引起酒精或有机磷农药的毒性发生改变.因此,仅仅根据酒精或有机磷农药的口服致

Abstract: To estimate the toxicity according to simple chemical is not helpful when severa materials bave??en taken in the forensis cases. The purpose of this tudy is to investigate the effects of the interaction of alcohol + DDVP, alcohol +trichlorfon, alcohol+methamicophos and alcohol+dimethoate in mouse. As a results: the LD50 of alcohol, DDVP, trichlorfon,methamidophos and imethoate were 9501, 71.97, 441. 2, 10.00 and 182.8mg/kg respectively.For the alcohol + DDVP, alcohol + trichlorfon,alcohol+methamidophos and alcohol+ dimethoate the LD50 measured were 5044, 5622, 3281 and 8281 mg/kg and the LD50 expected were 909.1, 5000, 5000 and 5000 mg/kg, hence the ratio of them (LD50 expected/LD50 measured) were 0.1802, 0.8894, 1.5239 and 0.6038 respectively. It is concluded that there is an antagonistical effect of interaction for alcohol+DDVP and an additive effect of interaction for alcohol+trichlorfon,alcohol+methamidophos and alcohol+dimethoate.

朱广友;颜零;卜俊;邓丽平;. 酒精与几种常见有机磷农药联合毒性的研究[J]. 法医学杂志, 1987, 0(1): 5-8.

ZHU GUANGYOU;YAN LING;BU JUN;DENG LIPING. Effect of Interaction of Alcohol Combined with Commonly Used Organohposphates Pesticides.[J]. , 1987, 0(1): 5-8.