法医学杂志

法医学杂志 ›› 1992, Vol. 0 ›› Issue (4): 148-150+.

• 论文 • 上一篇    下一篇

上海地区人体精子黄递酶_Ⅲ型的遗传多态性研究

周月琴;吴文庆;胡三多;张其英;   

  1. 上海医科大学法医学教研室,上海医科大学法医学教研室,上海医科大学法医学教研室,上海医科大学法医学教研室 上海200032,上海200032,上海200032,上海200032
  • 发布日期:1992-08-25 出版日期:1992-08-28

INVESTIGATION ON THE GENETIC POLMORPHISM OF DIA_3 IN MAN IN SHANGHAI DISTRICT

ZHOU YUE QIN. WU WEN QING. HU SANDUO. ZHANG QI YING DEPT. OF FORENSICSCIENCE, SHANGHAI MEDICAL UNIVERSITY   

  • Online:1992-08-25 Published:1992-08-28

被引次数

6

摘要： <正> Straub提纯一种与NADH或NADPH氧化有关的电子传递酶,具有黄素蛋白特性,命名为黄递酶(Diaphorase,DIA).Caldwell等首先报导了黄递酶的遗传多态性,可分1-1型、2-1型和2-2型三型,由一对共显性基因控制,作者认为此酶为精子细胞和睾丸组织所特有,称为精子黄递酶(sperm diaphorase,SD).Frsher等报导了黄递

Abstract: We investigated the polymorphism of sperm diaphorase Ⅲ with modified mixed starch gel eletrophoresis and PAGIEF.Among the 378 Chinese adult males in Shanghai population, three phenotypes wrer observed and the gene frequencies of DIA_3 wrer calculted as DIA_3~1 0.7275, DIA_3~2 0.2725(by SGE) and BIA_2~1 0.7228,DIA_3~2 0.2744 and DIA_3~v 0.0054(by PAGIEF).The IEF method is applied to phentype DIA_3 in seminal stain,which phenotypes are demostrated for up to 7 weeks at room temperature and for 11 weeks at 4℃. The DIA~3 in all 30 vaginal swabs were not typed by SGE and 1EF.