法医学杂志

法医学杂志 ›› 1993, Vol. 0 ›› Issue (3): 137-138+.

• 论文 • 上一篇    下一篇

固液萃取——导数紫外光谱法测定血中氯敌鼠

姜兆林;谭家镒;   

  1. 中国刑警学院法化系,中国刑警学院法化系 沈阳:110000,沈阳:110000
  • 发布日期:1993-06-25 出版日期:1993-06-28

QUANTITATIVE DETERMINATION OF CHLOROPHACINONE IN HUMAN BLOOD BY SOLIDPHASE EXTRACTION AND DERIVATIVE SPECTRHOTOMETRY

JIANG ZHAO—LIN TAN JIA—YI (THE THRID DEPT.CHINA CRIMINAL POLICE COLLEGE SHENYANG 110035)   

  • Online:1993-06-25 Published:1993-06-28

摘要： 氯敌鼠是国内近几年使用的杀鼠剂之一,化学结构属茚满二酮类。在司法鉴定实践中,时有因误吸。投毒氯敌鼠引起的中毒案件发生,而国内对氯敌鼠中毒检验的研究甚少。本文运用固液提取技术和导数紫外光谱技术,对生物检材中氯敌鼠的测定进行了实验研究。结果表明:方法简便、快速、可靠。

关键词: 氯敌鼠, 固液萃取, 导数光谱

Abstract: In this paper,a method quantitative determination of chlere—phacinone in human blood based on solid—phase extracion and derivative spectrophotometry has been developed.This method,using diuting sodium hydroxide solution as a diluent for posioning human blood,and directly extracting the diluted blood GDX 403(polymeric resine made in China),was sufficiently simple,rapid and depend- able.The results of this method were also reliable.Recoveries of chlorophacinone form spiked human blood were 73.5±5.0%,78.7±3.8%,80.8±4.0%(n=5)for the levels of 2ug/ml,10 ug/ml and 40 ug/ml respectly.

Key words: Chlorophacinone, Solid—phase extraction, Derivative spectrophotometry, blood.