法医学杂志

法医学杂志 ›› 2006, Vol. 0 ›› Issue (2): 101-103.

• 论文 • 上一篇    下一篇

大鼠死后腓肠肌直接电兴奋性变化与早期死亡时间的关系

李斌;闫红涛;陈伟杰;吴敬杰;廖诗平;廖志钢;   

  1. 四川大学华西基础医学与法医学院法医病理学教研室,四川大学华西基础医学与法医学院法医病理学教研室,四川大学华西基础医学与法医学院法医病理学教研室,四川大学华西基础医学与法医学院法医病理学教研室,四川大学华西基础医学与法医学院机能学实验室,四川大学华西基础医学与法医学院法医病理学教研室 四川成都610041,四川成都610041,四川成都610041,四川成都610041,四川成都610041,四川成都610041
  • 发布日期:2006-04-25 出版日期:2006-04-28

To Estimate Early Postmortem Interval by Investigating Changes of Rats′ Gastrocnemius Excitability

LI BIN, YAN HONG-TAO, CHEN WEI-JIE, WU JING-JIE, LIAO SHI-PING, LIAO ZHI-GANG (WEST CHINA SCHOOL OF BASIC MEDICINE AND FORENSIC SCIENCES OF SICHUAN UNIVERSITY, CHENGDU 610041, CHINA)   

  • Online:2006-04-25 Published:2006-04-28

摘要： 目的探讨大鼠死亡后不同时间腓肠肌电兴奋性的变化,为早期死亡时间的推断提供新的指标。方法建立大鼠机械性窒息模型,利用电生理检测仪检测死亡后不同时间大鼠腓肠肌对不同强度的电刺激的反应性,记录肌肉组织动作电位出现时间,统计学分析其差异并建立回归方程。结果大鼠机械性窒息死亡后一定时间内,其腓肠肌对电刺激的兴奋性与死亡时间呈明显线性关系。结论肌肉组织的电兴奋性可以作为早期死亡时间推断的有效指标。

关键词: 死亡时间推断, 腓肠肌, 电兴奋性, 法医学

Abstract: Objective To investigate the changes of excitability of rats′ gastrocnemius after rats were died from mechanic asphyxia, so as to make an objective evidence for estimating of the early postmortem interval. Methods After rats were sacrificed by mechanic asphyxia, the reaction of rats′ gastrocnemius to variable electric stimulation at different period after death were recorded by electricphysiological method.Results Changes in the properties of excitable tissue to electric stimulate in rats′ gastrocnemius after mechanic asphyxia seems to be well correlated with the early postmortem interval and appeared a linear relation in certain period. Conclusion The regular changes of excitability in muscle might be a useful means for estimating of early postmortem interval.

Key words: estimating of postmortem interval, gastrocnemius, electric excibility, forensic medicine