法医学杂志 ›› 2006, Vol. 0 ›› Issue (6): 445-447.

• 论文 • 上一篇    下一篇

过敏性休克死亡法医学诊断的研究现状

高彩荣;薛少华;王英元;   

  1. 山西医科大学法医学院,山西医科大学法医学院,山西医科大学法医学院 山西太原030001,山西太原030001,山西太原030001
  • 发布日期:2006-12-25 出版日期:2006-12-28

Present Study on the Forensic Medicine Diagnosis of the Sudden Erethistic Death

GAO CAI-RONG, XUE SHAO-HUA, WANG YING-YUAN (SCHOOL OF FORENSIC MEDICINE,SHANXI MEDICAL UNIVERSITY, TAIYUAN 030001, CHINA)   

  • Online:2006-12-25 Published:2006-12-28

摘要: 过敏性休克死亡在临床医学及法医学鉴定中较为常见,但过敏性猝死的死后诊断一直是法医病理学鉴定的一大难点。近年来,国内外学者研究了过敏性死亡血清IgE、组胺、肥大细胞类胰蛋白酶和P物质的含量以及其在肺脏和胃肠等组织中的免疫表达,试图为过敏性猝死的法医学鉴定提供客观、准确的形态学依据和诊断指标。本文就过敏性休克死亡法医学诊断的研究进展和存在的问题加以综述。

关键词: 过敏性猝死, IgE, 肥大细胞类胰蛋白酶, P物质, 免疫组化

Abstract: The death caused of anaphylactic shock is common in clinical medicine and medicolegal expertise, but it is a nodus to diagnose sudden death from allergy. In recent years, to provide objective and precise morphological evidence and index of diagnosis for sudden death from allergy, scholars of internal and overseas studied the content of IgE, HT, mast cell tryptase and SP in the serum of the death died of anaphylactic shock, and their immune express in lung and stomach intestine. In this text we reviewed the present study and existing problems of the forensic medicine diagnosis of the sudden erethistic death.

Key words: sudden death from allergy, IgE, mast cell tryptase, substance P, immunohistochemistry