法医学杂志

法医学杂志 ›› 2007, Vol. 0 ›› Issue (4): 274-276.

• 论文 • 上一篇    下一篇

液基细胞学技术对减少临床医疗纠纷的应用价值

刘宝琴;颜召文;姚红霞;蔡继锋;   

  1. 上海交通大学医学院,上海交通大学医学院,同济大学医学院,中南大学湘雅医学院 上海200025,上海200025,上海200040,湖南长沙410078
  • 发布日期:2007-08-25 出版日期:2007-08-28

Evaluation of Liquid Based Cytology Test(LCT) in Avoiding Medical Tangles

LIU BAO-QIN1,YAN ZHAO-WEN1,YAO HONG-XIA2,CAI JI-FENG3(1.MEDICAL COLLEGE OF SHANGHAI JIAOTONG UNIVERSITY,SHANGHAI 200025,CHINA;2.MEDICAL COLLEGE OF TONGJI UNIVERSITY,SHANGHAI 200040,CHINA;3.XIANGYA SCHOOL OF MEDICINE,CENTRAL SOUTH UNIVERSITY,CHANGSHA 41007   

  • Online:2007-08-25 Published:2007-08-28

被引次数

17

摘要： 目的探讨液基细胞学技术对于减少临床医疗纠纷的价值。方法对1531例样本分别用液基细胞学方法和传统巴氏涂片技术进行宫颈细胞学涂片制作,其中液基细胞学方法分别用新柏氏耗材和昂佰氏耗材;涂片根据TBS 2001标准进行诊断;细胞学诊断为LSIL以上病变(包括LSIL、HSIL、SCC和AC)者组织活检进行组织学诊断;应用SPSS11.0软件进行数据分析。结果液基细胞学方法同传统巴氏方法相比,在标本满意度、敏感度、特异度和准确性、假阴性率和误诊率等方面有显著统计学差异(P<0.05),新柏氏和昂佰氏获得结果之间无明显差异。结论液基细胞学技术可以有效提高宫颈癌普查的诊断水平,从而有效防止和减少医疗纠纷的发生;昂佰氏耗材可以替代新柏氏耗材进行液基细胞学检查。

关键词: 液基细胞学, 巴氏涂片, 医疗纠纷, 薄层细胞学制片, 宫颈癌

Abstract: Objective To evaluate of liquid based cytology test(LCT) in avoiding medical tangles.Methods One thousand five hundred five thirty one cases,which were collected from out-patients of precancerous lesions of uterine cervix,were randomly divided into three groups based on different smear preparation:LCT method was used in two groups(one with ThinPrep R kit and one with ArtoBrain R kit),conventional Papauicolaou smear(PS) was used in one group.All cases of abnormal cervical smears were identified by cytologic test underwent colposcopic examination and colopscopically multiple biopsy.Results of test were analyzed by software SPSS 11.0.Results Significant diference were found between LCT method and PS method compared by index of satifacation,sensitivity,specificity,accuracy,false negative rate and erroneous diagnosis rate(P<0.05,but no difference were found between two LCT groups(ThinPrep R kit and ArtoBrain R kit).Conclusion LCT method can improve diagnostic level of precancerous lesions of uterine cervix either tested by ThinPrep R kit or ArtoBrain R kit,so have the powerfull value to avoid medical tangles.

Key words: liquid based cytology test(LCT), papauicolaou smear, medical tangle, thin-preparation cytology test(TCT), cervical cancer