法医学杂志

法医学杂志 ›› 2016, Vol. 32 ›› Issue (3): 219-221.DOI: 10.3969/j.issn.1004-5619.2016.03.015

• 研究简报 • 上一篇    下一篇

甘肃东乡族男性24个Y-STR基因座遗传多态性（英文）

骆继怀1，2，孙红兵1，2，杨  鑫1，2，哈  飞1，2，张子龙1   

  1. （1. 甘肃省证据科学技术研究与应用重点实验室，甘肃 兰州 730070； 2． 兰州市公安局刑事科学技术研究所，甘肃 兰州 730030）
  • 发布日期:2016-06-25 出版日期:2016-06-28

Genetic Polymorphism of 24 Y-STR Loci in Dongxiang Ethnic Minority Male Residents in Gansu Province of China

LUO JI-HUAI1,2, SUN HONG-BING1,2, YANG XIN1,2, HA FEI1,2, ZHANG ZI-LONG1   

  1. （1. Key Laboratory of Evidence of Science and Technology Research and Application, Gansu Province, Lanzhou 730070, China; 2. Institute of Criminal Science and Technology, Lanzhou Public Security Bureau, Lanzhou 730030, China）
  • Online:2016-06-25 Published:2016-06-28
  • Contact: SUN Hong-bing, professor, major in forensic genetics; E-mail: sunhb.good@163.com
  • About author:LUO Ji-huai （1983—）, M.D, major in forensic genetics; E-mail: lanzhouDNA110@126.com
  • Supported by:

    the Youth Science and Technology Foundation of Gansu Province （1308RJYA059）, Technology research projects of Gansu Provincial Public Security （2016JSYJ01）, National Natural Science Foundation （81302622）.

摘要： 目的 检测24个Y-STR基因座单倍型的遗传多态性，探讨其法医物证学应用价值。 方法 应用AGCU Y24试剂盒和3130xl型遗传分析仪对154例甘肃东乡族男性无关个体的24个Y-STR基因座（DYS391、DYS389Ⅰ、DYS439、DYS389Ⅱ、DYS438、DYS643、DYS456、DYS458、DYS437、DYS635、DYS448、DYS527a/b、Y-GATA-H4、DYS447、DYS19、DYS392、DYS522、DYS393、DYS388、DYS390、DYS385a/b、DYS444）进行检测，获得其基因型分布情况。 结果 154例样本中共检出153种单倍型，单倍型多样性为0.991 5和个体识别率为0.994 0。 结论 24个Y-STR复合扩增体系具有较高单倍型遗传多态性和个体识别率。

关键词: 法医遗传学；多态现象, 遗传；Y染色体；短串联重复序列；单倍型；甘肃；东乡族

Abstract: Objective To determine the genetic polymorphism of 24 Y-STR loci haplotype and investigate its application value in legal physical evidence. Methods AGCU Y24 kit and 3130xl Genetic Analyzer were used to detect the distribution of 24 Y-STR loci including DYS391, DYS389Ⅰ, DYS439, DYS389Ⅱ, DYS438, DYS643, DYS456, DYS458, DYS437, DYS635, DYS448, DYS527a/b, Y-GATA-H4, DYS447, DYS19, DYS392, DYS522, DYS393, DYS388, DYS390, DYS385a/b and DYS444 in 154 unrelated individuals of Dongxiang ethnic minority males in Gansu province of China. Results A total number of 153 haplotypes were detected in 154 samples, the haplotype diversity was 0.991 5 and the discrimination power was 0.994 0. Conclusion The 24 Y-STR loci system has high haplotype diversity and discrimination power.  

Key words: forensic genetics, polymorphism, genetic, Y chromosome, short tandem repeat sequences, haplotype, Gansu, Dongxiang Population

中图分类号: