法医学杂志 ›› 2006, Vol. 0 ›› Issue (6): 417-420.

• 论文 • 上一篇    下一篇

用VBA语言开发群体遗传学统计分析软件

蔡颖;周霓;许业莉;相大鹏;苏建晖;张林田;   

  1. 广东恒正司法鉴定中心,汕头市中心医院,广东恒正司法鉴定中心,广东恒正司法鉴定中心,广东恒正司法鉴定中心,广东恒正司法鉴定中心 广东汕头515031,广东汕头515031,广东汕头515031,广东汕头515031,广东汕头515031,广东汕头515031
  • 发布日期:2006-12-25 出版日期:2006-12-28

Develop a Statistics Analysis Software in Population Genetics Using VBA Language

CAI YING1, ZHOU NI2, XU YE-LI1, XIANG DA-PENG1, SU JIANG-HUI1, ZHANG LIN-TIAN1 (1.GUANGDONG HENGZHENG FORENSIC IDENTIFYING CENTER, SHANTOU 515031, CHINA; 2. SHANTOU CENTRAL HOSPITAL, SHANTOU 515031, CHINA)   

  • Online:2006-12-25 Published:2006-12-28

摘要: 目的开发适用于短串联重复序列(STR)基因座群体遗传学统计分析的软件,促进和加快STR基因座群体遗传学基础研究。方法选用简单易用的MicrosoftVBAforExcel语言,利用宏功能,开发STR基因座群体遗传学统计分析软件。结果开发建立了基于VBA语言的“群体遗传学分析易”软件,能进行STR基因座群体遗传学分析。结论开发的基于VBA语言的“群体遗传学分析易”软件,具有计算统计功能完善、输入格式兼容性好、使用方便、输出格式清晰易懂的特点,可在国内外STR基因座群体遗传学研究领域推广应用。

关键词: 短串联重复序列(STR), 群体遗传学, 软件, Hardy-Weinberg平衡, 连锁平衡, VBA

Abstract: Objective To develop a statistics analysis software that can be used in STR population genetics for the purpose of promoting and fastening the basic research of STR population genetics. Methods Selecting the Microsoft VBA for Excel, which is simple and easy to use, as the program language and using its macro function to develop a statistics analysis software used in STR population genetics. Results The software "Easy STR Genetics" based on VBA language, by which the population genetic analysis of STR data can be made, were developed. Conclusion The developed software "Easy STR Genetics" based on VBA language, can be spread in the domain of STR population genetics research domestically and internationally, due to its feature of full function, good compatibility for different formats of input data, distinct and easy to understand outputs for statistics and calculation results.

Key words: short tandem repeats (STR), population genetics, software, Hardy-Weinberg equilibrium (HWE), linkage equilibrium, VBA