孕早期绒毛膜6—PGD多态性研究及西安地区144例6—PGD分型调查

法医学杂志 ›› 1987, Vol. 0 ›› Issue (2): 6-9.

孕早期绒毛膜6—PGD多态性研究及西安地区144例6—PGD分型调查

李小明;刘明俊;

西安医科大学法医学系,西安医科大学法医学系,

发布日期:1987-04-25 出版日期:1987-04-28

6—PGD POLYMORPHISM ANALYSIS OF FIRST—TRIMESTER CHORIONIC VILLI AND TYPING IN THE HANS OF XI'AN

LI XIAOMING LU MINGJUN (DEPARTMENT OF FORENSIC MEDICINE, XI'AN MEDICAL UNIVERSITY)

Online:1987-04-25 Published:1987-04-28

摘要/Abstract

摘要： <正> Simoai等人(1983)最先对妊娠首三月的绒毛进行染色体分析及酶测定。为了解决孕早期亲权鉴定,近年来,胡炳蔚和李生斌对妊娠6—11周活体绒毛进行了酸性磷酸酶(ACP)和脂酶D(EsD)多态性研究,马虹和刘勇等人先后报道从早孕绒毛细胞中检出ABO(H)血型物质

Abstract: Genetic heterogeneity of glucosephosphate dehydrogenase (6—PGD) from firststrimester chorionic villi and frequencies of the Hans of Xi'an was analysed by starch-gel electrophoresis. The Studies demonstrates that genetic heterogeneity of 6—PGD has existed in first trimester chorionic villi, the bands of it can be of equal intensity to the erythrocyte samples. In our population samples (n=144) the following frequencies were calculated: PGDA=0.8570, PGDc=0.1424 and DP=0.40. It may be regarded as one of the more stable genetic markers. It is of great value that the polymorphism is used for paternity test of first-trimester pregnancy and identificantion.

李小明;刘明俊;. 孕早期绒毛膜6—PGD多态性研究及西安地区144例6—PGD分型调查[J]. 法医学杂志, 1987, 0(2): 6-9.

LI XIAOMING LU MINGJUN (DEPARTMENT OF FORENSIC MEDICINE;XI'AN MEDICAL UNIVERSITY). 6—PGD POLYMORPHISM ANALYSIS OF FIRST—TRIMESTER CHORIONIC VILLI AND TYPING IN THE HANS OF XI'AN[J]. , 1987, 0(2): 6-9.