法医学杂志

法医学杂志 ›› 1987, Vol. 0 ›› Issue (2): 10-18.

• 论文 • 上一篇    下一篇

中国人(辽宁地区)PGM_1亚型的分布及一例PGM_1china罕见型的报导

王嵬;贾静涛;   

  1. 中国医科大学法医学系法医血清学教研室,中国医科大学法医学系法医血清学教研室,
  • 发布日期:1987-04-25 出版日期:1987-04-28

Distribution of Phosphoglucomutase-1(PGM1) subtype in Chinese with a Special Reference to the PGM_1 China Variant

WANG WEI, JIA JING TAO DEPARTMENT OF FORENSIC SEROLOGY, FACULTY OF FORENSIC MEDICINE CHINA MEDICAL UNIVERSITY,   

  • Online:1987-04-25 Published:1987-04-28

被引次数

1

摘要： <正> 1964年Spencer, Hopkinson及Harris在用淀粉凝胶电泳对人类红细胞内酶类的研究中首次检测出由PGM_11位点上的两个常见等位基因(PGM_11和PGM_12)所决定的3个常见表现型:PGM_1~1、PGM_1~2及PGM_12—1。后来,不少学者对PGM_1进,行了进一步的研究,相继发现了一些罕见等位

Abstract: A total of 320 unrelated individuals from the Liaoning area, China, have been t ped for red cell PGM_1 using isoelectric focusing(PH5—7) in thin—layer polyacry lamide gels. 10 subtypes are considered as gene products of 4 alleles at PGM_1 locus with the following frequencies. PGM_1~(1+)=0.6240, PGM_1~(1-)=0.1240,PGM_1~(2+)=0.1755, PGM_1~(2-)=0.0765. A rare variant PGM_1~(8) as well as a new rare variant PGM_1 China is reported and the pedigree study about this new variant has been carried out. T hePI of this new variant is also determined. The discriminatingpowe(DP) of the PGM_1 is 0.76. A example of the application PGM_1 in individual identification case is attached to this paper.