法医学杂志

法医学杂志 ›› 1998, Vol. 0 ›› Issue (2): 76-78+1.

• 论文 • 上一篇    下一篇

头发中检验海洛因代谢物应用于吸毒时间的推断

卓先义,吴侔天,洪战英   

  1. 司法部司法鉴定科学技术研究所!上海,200063,司法部司法鉴定科学技术研究所!上海,200063,第二军医大学药学院!上海,200433
  • 发布日期:1998-04-25 出版日期:1998-04-28

The history of heroin abuse by assaying 6-MAM and MOR in human hair

ZHUO XIANYI, WU MOUTIAN, HONG ZHANYING (1.INSTITUTEOF FORENSIC SCIENCES, MINISTRY OF JUSTICE, SHANGHAI200063, 2.COLLEGE OF PHARMACY THE SECOND MILITARYMEDICAL UNIVERSITY, SHANGHAI 200433)   

  • Online:1998-04-25 Published:1998-04-28

被引次数

5

摘要： 运用气／质联用-选择离子（GC／MS－SIM）技术对吸食或注射海洛因嫌疑人的头发进行分段分析，根据各段头发中是否检出6-单乙酰吗啡和吗啡，并结合头发的生长速度对吸毒时间作出大致推断。该方法专一性较好，检出下限0．5ng／mg，能够推断出剪取吸毒嫌疑人头发前几个月或某一个时期内是否经常性服用海洛因。

关键词: 头发检验, 海洛因, 单乙酰吗啡, 吗啡, 气-质联用法, 吸毒时间

Abstract: The purpose of this study is to conclude the historyof heroin abuse by assaying 6-monoacetylmorphine(MAM) and morphine (MOR) in human hair. The hair ofheroin abuse was labeled and segmented, then washedand cut into fragments. After hydrolyses and extraction,6-MAM and MOR in human hair were determined byGC/MS-SIM with selected ion monitoring. Results of thesegmented hair were analyzed. It provided usefulinformation about the history of heroin abuse (hairgrowth rate 1-1.5cm/mon).

Key words: heroin abuse, 6-monoacetylmorphine (MAM), morphine (MOR)