法医学杂志 ›› 2004, Vol. 0 ›› Issue (2): 116-119.

• 论文 • 上一篇    下一篇

卡方检验和精确检验在HWE检验中的应用

黄代新,杨庆恩   

  1. 华中科技大学同济医学院法医学系,华中科技大学同济医学院法医学系 湖北武汉430030 ,湖北武汉430030
  • 发布日期:2004-04-25 出版日期:2004-04-28

Application of chi-square test and exact test in Hardy-Weinberg equilibrium testing

HUANG DAI-XIN, YANG QING-EN (FACULTY OF FORENSIC MEDICINE, TONGJI MEDICAL COLLEGE, HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, WUHAN 430030,CHINA)   

  • Online:2004-04-25 Published:2004-04-28

摘要: 综述了几种不同数据处理方法卡方检验和精确检验在法医人类遗传标记群体遗传学研究Hardy-Wein鄄berg平衡检验中的应用。强调了精确检验在多等位基因标记系统,尤其是以VNTR、STR为代表的法医DNA分析研究中的重要性。

关键词: 群体遗传学, Hardy-Weinberg平衡, 卡方检验, 精确检验

Abstract: This article review the application of chi-square test of various data handling methods and exact test in Hardy-Weinberg equilibrium testing of human genetic marker in population genetics. The importance of HWE-exact test in multiallelic system was emphasized, especially in the study of forensic VNTR and STR typing.

Key words: population genetics, Hardy-Weinberg equilibrium, chi-square test, exact test