法医学杂志 ›› 2017, Vol. 33 ›› Issue (1): 20-23.DOI: 10.3969/j.issn.1004-5619.2017.01.005

• 论著 • 上一篇    下一篇

眼损伤图形刺激对比度视诱发电位

王  萌,俞晓英,陈捷敏,刘瑞珏,夏文涛   

  1. (司法部司法鉴定科学技术研究所 上海市法医学重点实验室 上海市司法鉴定专业技术服务平台,上海 200063)
  • 发布日期:2017-02-25 出版日期:2017-02-28
  • 作者简介:王萌(1976—),女,硕士,主检法医师,主要从事法医临床学研究;E-mail:1245647130@qq.com
  • 基金资助:

    中央级科研院所基本科研业务费资助项目(GY2013G-6);上海市法医学重点实验室资助项目(14DZ2270800);上海市司法鉴定专业技术服务平台资助项目(16DZ2290900)

Contrast Visual Evoked Potentials under Pattern Stimulus in Ocular Trauma

WANG MENG, YU XIAO-YING, CHEN JIE-MIN, LIU RUI-JUE, XIA WEN-TAO   

  1. (Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Institute of Forensic Science, Ministry of Justice, PRC, Shanghai 200063, China)
  • Online:2017-02-25 Published:2017-02-28

摘要: 目的 研究眼损伤者对比度视诱发电位的特征。 方法 选取本中心行法医临床学鉴定的60例眼损伤者,根据最佳矫正视力分为0.2~0.3(A组)、0.3~0.5(B组)、≥0.5(C组)三组。分别观察100%、25%、10%对比度条件下的对比度视诱发电位波的振幅及潜伏期变化特征,并行统计学分析。 结果 (1)相同对比度时,P100波振幅随刺激视角的减小而降低;(2)相同刺激视角时,P100波振幅随对比度降低而降低,组间差异有统计学意义(P<0.05);(3)100%、25%对比度时,相同刺激视角(100% 7′视角除外),A组与B组差异无统计学意义(P>0.05);A组与C组、B组与C组随视力提高,P100波振幅增高(P<0.05);10%对比度15′刺激视角,P100波振幅随视力提高而增高(P<0.05);(4)相同对比度下,相同刺激视角时,P100波潜伏期随视力提高而缩短,但组间差异无统计学意义(P>0.05)。相同刺激视角时,随对比度降低,P100波潜伏期延长,但差异无统计学意义(P>0.05)。 结论 对比度视诱发电位有望成为评估对比度视力的方法之一。

关键词: 法医学, 眼损伤, 诱发电位, 视觉, 视力损伤者

Abstract: Objective To study the characteristic of contrast visual evoked potentials (CVEP) in patients with ocular trauma. Methods Sixty patients defined as ocular trauma by forensic clinical examination in our center were selected, and split into 0.2-0.3 (Group A), 0.3-0.5 (Group B) and ≥0.5 (Group C) according to the best corrected visual acuity. The variation characteristics of wave amplitude and latency of CVEP under 100%, 25% and 10% contrast were observed and analyzed statistically. Results (1) Under the same contrast, the wave amplitude of P100 decreased with the decrease of stimulus perspective. (2) Under the same stimulus perspective, the wave amplitude of P100 decreased with the decrease of contrast (P<0.05). (3) Under the contrast of 100% and 25% with the same stimulus perspective (except 100% 7′ perspective stimulus), the difference between group A and group B had no statistical significance (P>0.05). Between group A and group C, group B and group C, the wave amplitude of P100 gradually increased with the increase of vision (P<0.05). Under the contrast of 10% with 15′ stimulus perspective, the wave amplitude of P100 increased with the increase of vision (P<0.05). (4) Under the same contrast with the same stimulation perspective, the latency of P100 wave shortened with the increase of vision, while the difference had no statistical significance (P>0.05). Under the same stimulus perspective, the latency of P100 wave was prolonged with the decrease of contrast (P>0.05). Conclusion CVEP may become one of the possible methods for the evaluation of contrast visual acuity.

Key words: forensic medicine, eye injuries, evoked potentials, visual, visually impaired persons

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