法医学杂志 ›› 2019, Vol. 35 ›› Issue (5): 596-601.DOI: 10.12116/j.issn.1004-5619.2019.05.016

• 综述 • 上一篇    下一篇

微生物膜应用于水中尸体PMI推断的前景展望

韩晗, 刘卓鹰, 郭娟娟, 符晓亮, 何静, 郭亚东, 蔡继峰   

  1. 中南大学基础医学院法医系,湖南 长沙 410013
  • 发布日期:2019-10-25 出版日期:2019-10-28
  • 通讯作者: 蔡继峰,男,教授,博士研究生导师,主要从事法医昆虫学、法医微生物学、法医临床学、法医病理学研究;E-mail:cjf_jifeng@163.com
  • 作者简介:韩晗(1994—),女,硕士研究生,主要从事法医病理学研究;E-mail:583538543@qq.com
  • 基金资助:
    国家自然科学基金资助项目(81373249,81571855)

Prospects of Application of Microbial Biofilm to Estimate PMI of Corpses in Water

HAN Han, LIU Zhuo-ying, GUO Juan-juan, FU Xiao-liang, HE Jing, GUO Ya-dong, CAI Ji-feng   

  1. Department of Forensic Medicine, College of Basic Medicine, Central South University, Changsha 410013, China
  • Online:2019-10-25 Published:2019-10-28

摘要: 在法医病理学中,死亡时间推断一直是难点问题,而水中尸体的PMI推断至今仍缺乏有效方法。微生物膜是微生物在生长过程中附着于非生物或生物表面,由自身产生的胞外聚合物及其基质网包裹的具有三维结构的微生物群体。微生物群体在其发生发展过程中存在一系列的群落演替现象,这种附着在水中尸体表面的生物膜蕴含的微生物群落及其演替过程很可能成为推断水中尸体死亡时间的新依据。本文详细阐述了微生物膜的概念、分类、研究手段以及影响因素,并分析了其在水中尸体死亡时间推断中的应用前景,为该领域的研究提供新的思路。

关键词: 法医病理学, 生物膜, 死亡时间, 溺死, 综述

Abstract: In forensic pathology, the estimation of postmortem interval (PMI) has always been a difficult issue, and there is still lack of effective methods to estimate PMI of corpses in water. Microbial biofilm refers to the microbial population attached to non-biological or biological surfaces by microorganisms during microbial growth, that has a three-dimensional structure, surrounded by extracellular polymers and matrix networks created by itself. A series of community succession phenomena of microorganisms occur during the occurrence and development of microbial population. The microbial community and its succession process of this kind of biofilm attached to the surface of a corpse in water may become a new basis for estimation of the PMI of corpses in water. This review elucidates on the concept, classification, research methods, and influencing factors of biofilm and analyzes its application prospects in PMI estimation of corpses in water, which would provide new ideas for the researches in this field.

Key words: forensic pathology, biofilms, postmortem interval, drowning, review