法医学杂志 ›› 2020, Vol. 36 ›› Issue (3): 365-368,373.DOI: 10.12116/j.issn.1004-5619.2020.03.013

• 综述 • 上一篇    下一篇

外伤性癫痫生物标志物的研究进展

贾孝1,2, 周凤娟1,2, 代滨滨1,2, 王旭1,2, 杨天潼1,2   

  1. 1. 中国政法大学证据科学教育部重点实验室,北京 100088; 2. 司法文明协同创新中心,北京 100088
  • 发布日期:2020-06-25 出版日期:2020-06-28
  • 通讯作者: 杨天潼,男,博士,副教授,主要从事法医临床学和法医病理学研究;E-mail:yangtiantong@126.com
  • 作者简介:贾孝(1994—),女,硕士,主要从事法医临床学研究;E-mail:794001305@qq.com

Progress in Research on Biomarkers of Post-Traumatic Epilepsy

JIA Xiao1,2, ZHOU Feng-juan1,2, DAI Bin-bin1,2, WANG Xu1,2, YANG Tian-tong1,2   

  1. 1. Key Laboratory of Evidence Science, Ministry of Education, China University of Political Science and Law, Beijing 100088, China; 2. Center of Cooperative Innovation for Judicial Civilization, Beijing 100088, China
  • Online:2020-06-25 Published:2020-06-28

摘要: 外伤性癫痫(post traumatic epilepsy,PTE)是创伤性脑损伤的严重并发症,是法医学鉴定实践的疑难问题。近年来,许多生物标志物被应用于损伤和疾病的诊断、治疗及预后。在癫痫研究领域现有许多PTE生物标志物的研究。本文就近年来有关PTE生物标志物的研究进展进行综述,以期对PTE的法医学鉴定提供借鉴。

关键词: 法医学;癫痫, 创伤后;生物标志物;综述

Abstract: Post traumatic epilepsy (PTE) is a serious complication of traumatic brain injury and a difficult problem in forensic justice practice. In recent years, many biomarkers have been applied to the diagnosis, treatment and prognosis of injuries and diseases. There have been many studies on the biomarkers of PTE in the field of epilepsy. This paper reviews the progress in research on biomarkers of PTE in recent years in order to provide reference for the forensic identification of PTE.

Key words: forensic medicine, epilepsy, post-traumatic, biomarker, review