法医学杂志 ›› 1986, Vol. 0 ›› Issue (2): 16-20.

• 论文 • 上一篇    下一篇

人血清、血痕中HLA——A_2和HLA——B_(40)抗原的测定

程大霖;刘祖伯;   

  1. 司法部司法鉴定科学技术研究所,司法部司法鉴定科学技术研究所,
  • 发布日期:1986-04-25 出版日期:1986-04-28

Determination of HLA-A2 and HLA-B40 antigens in sera and dried bloodstains

CHENG DALIN LIU ZUBO (DEPARTMENT OF TATERIAL EVIDENCE ON FORENSIC SCIENCES, INSTITUTE OF FORENSIC SCIENCES, MINITRY OF JUSTICE, PRC.)   

  • Online:1986-04-25 Published:1986-04-28

摘要: <正> 具有复杂的遗传多态性的HLA(人类白细胞抗原)系统的实际应用正日益受到重视.在医学临床上,建立在HLA分型基础上的有关输血、器官移植、卵性诊断、疾病关联等研究和应用规模正日趋扩大和深入;在法医实践中,利用HLA分型进行亲子鉴定的工作也业已在国内开展. HLA的多态性,显现了其在作个人识别时具有极高的排除率.由于HLA不仅以

Abstract: The soluble HLA-AB antigens of the different dilution in sera and dried bloodstaims were determined with microlymphocytotoxicity inhibition test. Adopting lymphocytotoxicity 11 grades marks and useing 2 grades as the judgment standard of the inhibition, the test res- ults are satisfactory. With the groups of double-diluted anti-HLA sera, the soluble HLA-AB antigens in the maceration extracts of dried bloodstains of up to 1/80 dilution can be determined successfully.