法医学杂志

法医学杂志 ›› 1992, Vol. 0 ›› Issue (2): 62-64+9.

• 论文 • 上一篇    下一篇

辽宁地区汉族人群补体C_7遗传多型性研究

庞灏;丁梅;贾静涛;东朋子;恒成;茂行;   

  1. 中国医科大学法医系,中国医科大学法医系,中国医科大学法医系,日本国熊本大学医学部法医学教室,日本国熊本大学医学部法医学教室,日本国熊本大学医学部法医学教室 沈阳110001,沈阳110001,沈阳110001,日本 熊本,日本 熊本,日本 熊本
  • 发布日期:1992-04-25 出版日期:1992-04-28

GENETIC POLYMORPHISM 0F THE SEVENTH COMPONENT 0F COMPLE-MENT IN NORTHEAST CHINA

HAO PANG ET AL., FACULTY OF FORENSIC MEDICINE, CHINA MEDICAL UNIVERSITY, LIAONING, P. R. CHINA 110001 TOMOKO HIGASHI, SHIGEYUKI TSUNENARI, DAPARTMENT OF FORENSIC MEDICINE, KUMAMOTO UNIVERSITY MEDICAL SCHOOL, KUMAMOTO, JAPAN   

  • Online:1992-04-25 Published:1992-04-28

摘要： 本文应用薄层琼脂糖凝胶等电聚焦电泳结合免疫印迹技术,报道了辽宁地区汉族随机人群补体第七成分遗传多型性的分布,C7的基因频率为C~(1)_(7)=0.8251,C~(2)_(7)=0.1108,C~(3)_(7)=0.0320,C~(4)_(7)=0.0320,按Hardy·Weinberg法则进行吻合度检验,其观测值与期望值一致,文中并对与中国其它地区及与日本人群等位基因的差异性做了比较.

关键词: 补体C_7, 多型性, 基因频率, 琼脂糖凝胶等电聚焦

Abstract: The distribution of the seventh component of complement phenotypes were studied by using the thin agarose gel isoelectric focusing (AGIEF) foll-owing immunoblotting technique in 203 Chinese Han populations in Liaoning area. The gene frequ-encies were as follows: C7~1=0.8215, C7~2=0.1108, C7~3=0.032, C7~4=0.032, respectively. The observed numbers of the phenotypes were in agreement with the expected numbers under the Hardy-Weinberg equilibrium. The gene frequencies among three area in China, and Chinese and Japanese populationss were compared.