法医学杂志

法医学杂志 ›› 2003, Vol. 0 ›› Issue (1): 18-21.

• 论文 • 上一篇    下一篇

广泛软组织挫伤后器官形态学的研究

李戈,吕俊苞,姚青松,朱小曼,胡丙杰,罗斌   

  1. 广州市越秀区检察院,中山大学医学院法医系,广州市公安局刑事科学研究所,中山大学医学院法医系,中山大学医学院法医系,中山大学医学院法医系 广东 510037 ,广东广州 510080 ,广东 510000 ,广东广州 510080 ,广东广州 510080 ,广东广州 510080
  • 发布日期:2003-02-25 出版日期:2003-02-28

Morphological changes of tissues after extensive soft tissue injury

LI GE, LU JUN-BAO, YAO QING-SONG, ET AL. (PROCURATORATE OF YUEXIU DISTRICT,GUANGZHOU 510037;DE-PARTMENT OF FORENSIC PATHOLOGY,SUN YAT-SEN UNIVERSITY, GUANGZHOU 510089; THE CRIMINAL SCIENCES RESEARCH INSTITUTE OF POLICE BUREAU OF GUANGZHOU,GUANGZHOU 5   

  • Online:2003-02-25 Published:2003-02-28

摘要： 目的探索法医病理学诊断广泛软组织挫伤、挤压综合征致死案例的形态学改变。方法采用大鼠广泛软组织挫伤模型和人体挤压综合征致死标本,对器官进行HE染色、肾肌红蛋白HSP免疫组化染色及电镜观察。 结果肾肌红蛋白的阳性率分别为60％、75％、95％;心肌、脑组织阳性染色率为90％;广泛软组织挫伤短期内死亡的大鼠肾电镜观察,可见多种组织细胞病理改变致使毛细血管腔狭窄、闭塞等。结论建立了较理想的大鼠广泛软组织挫伤形成的挤压综合征动物模型;为此类研究积累了具有一定实用价值的病理形态学资料。

关键词: 广泛软组织挫伤, 肌红蛋白, 热休克蛋白, 免疫组织化学技术

Abstract: Objective To study the pathological morphological changes for diagnosing the cause of death of extensive soft tissue injury or crush syndrome. Methods The tissues were stained by HE and IHC. Results (1)The Mb positive rate was 60%,75%,95% respectively.(2)Both the HSP70 positive rate of hearts and brains were 90%. Conclusion (1 )The animal model of broad soft tissue injury was established.(2) Accumulated the pathological morphological data for diagnosing the cause of death of extensive soft tissue injury or crush syndrome.

Key words: soft tissue injury, myoglobin, heat shock protein, immunohistochemistry