法医学杂志

法医学杂志 ›› 1994, Vol. 0 ›› Issue (2): 0-0.

• 论文 •    

青壮年猝死综合征心肌肌红蛋白缺失的免疫组化研究

陈新山，胡俊，秦启生，黄光照   

  1. 同济区科大学法医病理学教研室
  • 发布日期:1994-04-25 出版日期:1994-04-28

AN IMMUNOHISTOCHEMICAL STUDY OF MYOGLOBIN DEPLETION FROM MYOCARDI UM IN THE CASES OF SUDDEN MANHOOD EDATH SYNDROME

CHEN XINSHAN; HU JUN;QIN QISHENG; HUANG GUANGZHAO (DEPARTMENT OF FORENSIC PATHOLOGY, TONGJI MEDICAL UNIVERSILY; WUHAN,430030)   

  • Online:1994-04-25 Published:1994-04-28

被引次数

10

摘要： 作者应用免疫组比技术（ＡＢＣ）对青壮年淬死综合征及对照组病例的心肌肌红：蛋白缺失情况进行了研究，并经扫描显微镜光度计测量分析，结果发现青壮年猝死综合征组心肌肉肌红蛋白均有不同程度的缺失，多数病例呈多发、散在、节段性分布，而对照组无明显缺失。认为这种多发、散在、节段性的肌红蛋白缺失与其仅有不同程度的心肌缺血而未出现大片心肌梗死有关，而这种不同程度的心肌缺血很可能为冠状动脉痉挛所致。

关键词: 青壮年猝死综合征, 肌红蛋白缺失, 免疫组织化学, ABC法

Abstract: Myoslobin (Mb) depletion from myocardium in the cases of Sudden Manhood Death Syndrome (SMDS) and control group was studied using an immunohistochemical technique (ABC method)Mb was detected quantitatively by using a scanning microscope photometer. The results show that there were clear depletion of Mb in each case of SADS, and mest of them were multiple, disseminated and segmental distribution, but there was hide las in the cases of control group. We suggested thst the multiple, disseminated and segmental depletion of Mb has relation to the fact of myocatdial ischenmia but without large area infarction in myocardium of the cases, and that the myocardial ischemia of the cases was probably pro duced by coronaryspasm.

Key words: Sudden Manhood Death Syndrome, Myoglobin depletion, Immunohistochemistry, ABC method