法医学杂志

法医学杂志 ›› 2004, Vol. 0 ›› Issue (3): 162-163+.

• 论文 • 上一篇    下一篇

中国鄂温克族人群15个STR基因座多态性研究

黄玉立,顾明波,王剑,杜庆新,李晓平,刘牧,沈淑萍,陈彩   

  1. 黑龙江省公安厅刑事技术处遗传室,黑龙江省公安厅刑事技术处遗传室,黑龙江省公安厅刑事技术处遗传室,黑龙江省公安厅刑事技术处遗传室,黑龙江省公安厅刑事技术处遗传室,内蒙古科技大学医学院,内蒙古科技大学医学院,内蒙古科技大学医学院 黑龙江哈尔滨150008 ,黑龙江哈尔滨150008 ,黑龙江哈尔滨150008 ,黑龙江哈尔滨150008 ,黑龙江哈尔滨150008 ,内蒙古包头014010 ,内蒙古包头014010 ,内蒙古包头014010
  • 发布日期:2004-06-25 出版日期:2004-06-28

A genetic study of 15 STR loci in Chinese E Wen-ke population

HUANG YU-LI,GU MMING-BO,WANG JIAN,ET AL.(CRIMINAL SCIENCE&TECHNOLOGY INSTITUTE OF HEI-LONGJIANG PROVINCE,HARBIN150008,CHINA)   

  • Online:2004-06-25 Published:2004-06-28

被引次数

15

摘要： 目的调查15个STR基因座在中国鄂温克族人群中的基因频率分布。方法应用PowerPlex16System复合扩增系统,对99名鄂温克族无关个的血样DNA进行多态性研究。结果在鄂温克族人群中15个STR基因座偶合率(Pm)在0.0205～0.1733之间,个体识别概率(DP)在0.8267～0.9795之间,杂合度在0.6061～0.9091之间,三联非父排除率(PE)在0.4038～0.7690之间,多态性信息总量(PIC)在0.5985～0.8734之间,15个STR基因座总TDP值为0.9999999999998,所有基因座经χ2检验符合Hard-Weinberg平衡。结论上述15个STR基因座在鄂温克族人群中等位基因分布较好,个体识别率高,适合法医个体识别和亲子鉴定。

关键词: 法科学, 鄂温克族, STR基因座, 复合扩增, 遗传多态性

Abstract: Objective To investigate the genetic polymorphisms of15STRs loci in Chinese E Wen-ke population.Methods DNA samples from99unrelated individuals in Chinese E Wen-ke population were screened by Power Plex16System and ABI3100Genetic Analyzer.Results The genotype frequencies of these15STR loci meet the Hardy-Weinberg expectation.The Matching probability of15STRs loci were between0.0205-0.1733,discriminating power(DP)at0.8267-0.9795,heterozygosity(Ho)at0.6061-0.9091,power of exclusion(PE)at0.4038-0.7690,polymorphism information content(PIC)at0.5985-0.8734.The total DP of15STRs loci is0.9999999999998.Conclusion Our results showed that the15STRs loci of Power Plex16System are valuable STR loci genetic marker system having high DP and are useful in forensic case work in Chinese E Wen-ke population.

Key words: forensic science, E Wenke population, STR loci, multiplexing PCR, genetic polymorphism