法医学杂志 ›› 2006, Vol. 0 ›› Issue (1): 81-83.

• 论文 • 上一篇    下一篇

月经血鉴定与基质金属蛋白酶-11

郑晶;陆惠玲;陈森;   

  1. 中山大学基础医学院法医物证学教研室,中山大学基础医学院法医物证学教研室,中山大学基础医学院法医物证学教研室 广东广州510080,广东广州510080,广东广州510080
  • 发布日期:2006-02-25 出版日期:2006-02-28

Menstrual Blood Identification and Matrix Metalloproteinase-11

ZHENG JING, LU HUI-LING, CHEN SEN (DEPARTMENT OF FORENSIC BIOLOGY, BASIS MEDICAL COLLEGE, SUN YAT-SEN UNIVERSITY, GUANGZHOU 510080,CHINA)   

  • Online:2006-02-25 Published:2006-02-28

摘要: 月经血鉴定是法医血痕检验的内容之一。本文就月经血鉴定的几种经典方法进行回顾,并分析其应用局限性。基质金属蛋白酶-11是一种能降解细胞外基质的水解蛋白酶,有研究提示基质金属蛋白酶-11以其在月经血中表达的特异性和检测方法的灵敏性有可能成为对月经血鉴定的新一代标志物。本文对基质金属蛋白酶-11的结构、功能、在月经血鉴定中的应用及展望进行综述。

关键词: 法医学, 月经血, 基质金属蛋白酶-11

Abstract: The identification of menstrual blood belongs to the forensic examination of bloodstains. The traditional methods for detecting menstrual blood were reviewed and their obstacles in forensic application were discussed. Matrix metalloproteinase-11 is a kind of protease which degrades the extracellular matrix. Some researches had indicated that matrix metalloproteinase-11 might be a new marker for specifically and sensitively detecting menstrual blood. The structure, function of matrix metalloproteinase-11 and its application in menstrual blood identification were reviewed.

Key words: forensic science, menstrual blood, matrix metalloproteinase-11