法医学杂志 ›› 2012, Vol. 28 ›› Issue (1): 28-31,35.DOI: 10.3969/j.issn.1004-5619.2012.01.007

• 论著 • 上一篇    下一篇

不同视野刺激时ERP及其分布特征

刘小琴,李倩倩,常  盼,陈溪萍   

  1. (苏州大学医学部法医学系,江苏 苏州 215123)
  • 发布日期:2012-02-25 出版日期:2012-02-28
  • 通讯作者: 通信作者:陈溪萍,女,主任法医师,硕士研究生导师,主要从事法医临床学教学、鉴定及视听电生理学研究;E-mail:xiping.chen@163.com
  • 作者简介:刘小琴(1984—),女,山西吕梁人,硕士研究生,主要从事法医临床学研究;E-mail:lxq0922qpg@163.com
  • 基金资助:

    国家自然科学基金面上项目(81172911)

Characteristics and Distribution of ERP by Different Field Stimulation

LIU XIAO-QIN, LI QIAN-QIAN, CHANG PAN, CHEN XI-PING   

  1. (Department of Forensic Medicine, Medical College of Soochow University, Suzhou 215123, China)
  • Online:2012-02-25 Published:2012-02-28

摘要: 目的 研究正常人不同视野刺激事件相关电位(event related potential,ERP)各波潜伏期和波幅变化及其在头皮的分布特征。 方法 分别对20名正常视功能受试者给予10°和60°两种不同视野刺激,同时在头皮记录ERP。 结果 两种不同视野刺激均能诱发出明显不同的外源性成分P1(70~125 ms)、N1(90~170 ms)和P2(140~220 ms),内源性成分N2(190~280 ms)和P3(290~430 ms)。两者比较,10°视野刺激时ERP各成分潜伏期较短,N1、N2波波幅较小且分布广泛,而枕颞区P1、额前区P2和枕区P3波波幅较高。 结论 两种不同视野刺激所诱发的ERP各波潜伏期、波幅及在头皮的分布均有显著差异,该差异反映不同视野刺激时人脑对视觉信息的整合、处理过程不同。

关键词: 法医学, 诱发电位, 视野

Abstract: Objective To study the variation of latency and amplitude of the event related potential (ERP) and its distribution in human scalp when the normal subjects were stimulated with different visual fields. Methods The ERP recorded in scalp with the stimulation of 10° visual field and 60° visual field respectively in 20 healthy volunteers with normal visual function. Results Two different visual field stimulation may evoke the different exogenous components P1(70-125 ms), N1(90-170 ms), P2(140-220 ms) and endogenous components N2(190-280 ms) and P3(290-430 ms). The latencies of all the components evoked by 10° visual field were shorter than that of the 60° visual field while the amplitudes of N1 and N2 were lower and appeared over the extensive encephalic region; and the amplitudes of the P1, P2 and P3 were higher and appeared in occipitotemporal, prefrontal and occipital region, respectively. Conclusion Two different visual field stimulation may evoke all the ERP components with significant differences in the latency, amplitude and distribution. The differences may reflect the different visual information integration and processing in human brain during the different visual field stimulation.

Key words: forensic medicine, evoked potentials, visual fields

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