›› 2001, Vol. 0 ›› Issue (4): 212-213.

• 论文 • Previous Articles     Next Articles

The changes of tryptase activity in anaphylactic shock guinea-pigs

GUO WEI, CHEN YU-CHUAN, LIU SHUI-PING,ET AL.(DEPARTMENT OF FORENSIC PATHOLOGY, SUN YAT-SEN UNIVERSITY OF MEDICAL SCIENCES, GUANGZHOU, 510080 )   

  • Online:2001-08-25 Published:2001-08-28

Abstract: Objective To investigate the changes of the activity of tryptase of sera, lungs and bronchial tubes in the guinea-pigs which suffered from hetero-serum anaphylactic shock. Methods Sera and tissues were collected from anaphylactic shock guinea-pigs,and the enzyme activity was tested colormetrically using special substrate,BAPNA.Results The activity of tryptase of sera,lungs and bronchial tubes increased significantly in Anaphylactic guinea-pigs compared with control group.Conclusion The changes of tryptase activity are helpful to diagnose anaphylactic shock.

Key words: anaphylactic shock, mast cell, tryptase, enzyme activity