GDNF expression following the severe brain injury in rats

Abstract

Abstract: Objective To evaluate the changes of GDNF after severe brain injury. Methods Changes GDNF in cortex, thalamus and pontine was observed by using immunohistochemistry and image analysis technique. Results The lever of GDNF was increasing at Id, reaching peak at 3d, not obviously decreasing at 5d and still higher than normal at 7d after severe brain injury. Conclusion As an objective indication, the time sequence regularity of GDNF after brain injury may be applied in brain injury time estimation.

Key words: glial cell line-derived neurotrophic factor, immunohistochemistry, brain injury

WANG XIN;LAO ZHI-GANG;LIU MIN;ET AL. (FORENSIC PATHOLOGY DEPARTMENT;SCHOOL OF LEGAL MEDICINE;SICHUAN UNIVERSITY;CHENGDU 00). GDNF expression following the severe brain injury in rats[J]. , 2003, 0(1): 1-3.

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GDNF expression following the severe brain injury in rats

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