The research progression of fibronectin EDA's expression and functions

Abstract

Abstract: Fibronectin is an adhesive extracellular matrix glycoprotein,it's primary gene transcription is alterna-tively spliced in three regions,designated EDA,EDB and IIICS.EDA segment potentiates the ability of FN to promote cell adhesion,migration,differentiation and proliferation,thus playing an important role in the process of wound healing,embryonic development and tumor metastasis.Here we discuss the alternatively splicing mecha-nism,biological properties and possible application of EDA.

Key words: fibronectin, EDA segment, expression and function

XUE AI-MIN;ZHAO ZI-QIN(DEPARTMENT OF FORENSIC MEDICINE;SHANGHAI MEDICAL SCHOOL;FUDAN UNIVERSITY;SHANGHAI000;CHINA). The research progression of fibronectin EDA's expression and functions[J]. , 2003, 0(3): 190-193.

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The research progression of fibronectin EDA's expression and functions

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