›› 2007, Vol. 0 ›› Issue (1): 18-19+2.

• 论文 • Previous Articles     Next Articles

Bcl-2 Expression Following the Brain Concussion in Rats

ZHU XU-YANG,WANG FENG,FANG WEI-HUA,WU MAO-WANG (DEPARTMENT OF FORENSIC MEDICINE,WANNAN MEDICAL COLLEGE,WUHU 241001,CHINA)   

  • Online:2007-02-25 Published:2007-02-28

Abstract: Objective To evaluate the expression of Bcl-2 protein after brain concussion.Methods Expression levels of Bcl-2 protein in cortex,pontine and cerebellum of rats were investigated using immunohistochemistry.Results There was no expression of Bcl-2 protein in control group seen.The expression of Bcl-2 protein in brain concussion groups was detected at 1hour,and the expression level reached its peak 4 days after the concussion and then declined gradually.Conclusion Our findings suggest that the detection of Bcl-2 protein could be an indicator for diagnosis of brain concussion and for estimation of the post injury time interval.

Key words: brain concussion, Bcl-2, immunohistochemistry