Abstract: Objective To evaluate of liquid based cytology test(LCT) in avoiding medical tangles.Methods One thousand five hundred five thirty one cases,which were collected from out-patients of precancerous lesions of uterine cervix,were randomly divided into three groups based on different smear preparation:LCT method was used in two groups(one with ThinPrep R kit and one with ArtoBrain R kit),conventional Papauicolaou smear(PS) was used in one group.All cases of abnormal cervical smears were identified by cytologic test underwent colposcopic examination and colopscopically multiple biopsy.Results of test were analyzed by software SPSS 11.0.Results Significant diference were found between LCT method and PS method compared by index of satifacation,sensitivity,specificity,accuracy,false negative rate and erroneous diagnosis rate(P<0.05,but no difference were found between two LCT groups(ThinPrep R kit and ArtoBrain R kit).Conclusion LCT method can improve diagnostic level of precancerous lesions of uterine cervix either tested by ThinPrep R kit or ArtoBrain R kit,so have the powerfull value to avoid medical tangles.

Key words: liquid based cytology test(LCT), papauicolaou smear, medical tangle, thin-preparation cytology test(TCT), cervical cancer