›› 2008, Vol. 0 ›› Issue (3): 214-220.

• 论文 • Previous Articles     Next Articles

Analysis of Genetics and Genomics of Short Tandem Repeat Loci Commonly Used in Kinship Testing

LI CHENG-TAO1,2, GUO HONG3, ZHAO ZHEN-MIN1, LI LI1 (1. SHANGHAI KEY LABORATORY OF FORENSIC MEDICINE, INSTITUTE OF FORENSIC SCIENCE, MINISTRY OF JUSTICE, P.R.CHINA, SHANGHAI 200063, CHINA; 2. SCHOOL OF LIFE SCIENCES, FUDAN UNIVERSITY, SHANGHAI 200433, CHIN   

  • Online:2008-06-25 Published:2008-06-28

Abstract: Since the foundation of FBI laboratory′s Combined DNA Index System (CODIS) a decade ago, the 13 CODIS STR loci of the system as well as the recently developed Penta D, Penta E, D2S1338 and D19S433 loci have been widely used by kinship testing laboratories worldwide and have played an important role in the field of Kinship Testing and in construction of criminal database. This article systemically analyzed the characteristics of STR loci information and its genomic information analyzed through search of a variety of database including Web of Knowledge, Elsevier and Internet resources. The up-to-date application of the commonly used STR loci in recent years is also reviewed.

Key words: forensic biology, genomics, combined DNA index system, STR loci