Journal of Forensic Medicine ›› 2023, Vol. 39 ›› Issue (3): 305-308.DOI: 10.12116/j.issn.1004-5619.2021.510909
Special Issue: 法医学亲子和亲缘关系鉴定专题
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Received:2021-09-28
Online:2023-07-29
Published:2023-06-25
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URL: http://www.fyxzz.cn/EN/10.12116/j.issn.1004-5619.2021.510909
| 基因座 | 分型 | IBS | FSI | 基因座 | 分型 | IBS | FSI | ||
|---|---|---|---|---|---|---|---|---|---|
| 姐姐 | 弟弟 | 姐姐 | 弟弟 | ||||||
| D3S1358 | 15/16 | 14/16 | 1 | 0.631 4 | FGA | 23/25 | 19/23 | 1 | 0.808 8 |
| D5S818 | 12/13 | 10/11 | 0 | 0.250 0 | D19S253 | 12/14 | 12/14 | 2 | 8.680 9 |
| D2S1338 | 23/23 | 23/23 | 2 | 8.772 5 | D6S477 | 13/13 | 13/16 | 1 | 1.453 1 |
| TPOX | 8/8 | 8/9 | 1 | 0.736 8 | GATA198B05 | 22/22 | 15/16 | 0 | 0.250 0 |
| CSF1PO | 7/13 | 12/13 | 1 | 1.988 5 | D15S659 | 12/13 | 12/17 | 1 | 0.825 2 |
| Penta D | 9/13 | 9/10 | 1 | 0.592 7 | D8S1132 | 17/23 | 17/22 | 1 | 1.466 0 |
| TH01 | 9/9 | 7/9 | 1 | 0.729 4 | D3S3045 | 13/14 | 9/13 | 1 | 0.853 9 |
| vWA | 14/14 | 14/18 | 1 | 1.223 9 | D14S608 | 11/14 | 7/14 | 1 | 24.759 8 |
| D7S820 | 10/11 | 10/12 | 1 | 1.014 5 | D17S1290 | 16/18 | 10/18 | 1 | 1.321 1 |
| D21S11 | 30/32.2 | 29/29 | 0 | 0.250 0 | D3S1744 | 14/15 | 14/18 | 1 | 1.640 4 |
| Penta E | 5/23 | 20/23 | 1 | 7.646 4 | D2S441 | 11/12 | 11/11 | 1 | 0.982 3 |
| D10S1248 | 13/13 | 13/15 | 1 | 0.908 6 | D18S535 | 9/13 | 12/13 | 1 | 0.875 9 |
| D8S1179 | 11/14 | 11/11 | 1 | 2.920 9 | D13S325 | 20/23 | 18/20 | 1 | 0.721 5 |
| D1S1656 | 14/16 | 12/16 | 1 | 0.843 3 | D7S1517 | 21/25 | 23/25 | 1 | 0.978 9 |
| D18S51 | 14/17 | 14/16 | 1 | 0.828 7 | D10S1435 | 12/13 | 12/12 | 1 | 0.909 8 |
| D12S391 | 18/21 | 19/21 | 1 | 1.250 0 | D11S2368 | 22/23 | 18/22 | 1 | 1.903 4 |
| D6S1043 | 11/13 | 11/18 | 1 | 1.392 6 | D4S2366 | 9/9 | 13/13 | 0 | 0.250 0 |
| D19S433 | 14/15.2 | 13/14 | 1 | 0.756 3 | D7S3048 | 21/23 | 20/21 | 1 | 1.288 2 |
| D16S539 | 10/11 | 10/11 | 2 | 5.495 4 | D5S2500 | 15/15 | 12/15 | 1 | 1.046 2 |
| D13S317 | 7/8 | 7/11 | 1 | 89.535 7 | |||||
Tab. 1 Typing results, IBS scores and FSI for 39 autosomal STRs of the elder sister and younger brother
| 基因座 | 分型 | IBS | FSI | 基因座 | 分型 | IBS | FSI | ||
|---|---|---|---|---|---|---|---|---|---|
| 姐姐 | 弟弟 | 姐姐 | 弟弟 | ||||||
| D3S1358 | 15/16 | 14/16 | 1 | 0.631 4 | FGA | 23/25 | 19/23 | 1 | 0.808 8 |
| D5S818 | 12/13 | 10/11 | 0 | 0.250 0 | D19S253 | 12/14 | 12/14 | 2 | 8.680 9 |
| D2S1338 | 23/23 | 23/23 | 2 | 8.772 5 | D6S477 | 13/13 | 13/16 | 1 | 1.453 1 |
| TPOX | 8/8 | 8/9 | 1 | 0.736 8 | GATA198B05 | 22/22 | 15/16 | 0 | 0.250 0 |
| CSF1PO | 7/13 | 12/13 | 1 | 1.988 5 | D15S659 | 12/13 | 12/17 | 1 | 0.825 2 |
| Penta D | 9/13 | 9/10 | 1 | 0.592 7 | D8S1132 | 17/23 | 17/22 | 1 | 1.466 0 |
| TH01 | 9/9 | 7/9 | 1 | 0.729 4 | D3S3045 | 13/14 | 9/13 | 1 | 0.853 9 |
| vWA | 14/14 | 14/18 | 1 | 1.223 9 | D14S608 | 11/14 | 7/14 | 1 | 24.759 8 |
| D7S820 | 10/11 | 10/12 | 1 | 1.014 5 | D17S1290 | 16/18 | 10/18 | 1 | 1.321 1 |
| D21S11 | 30/32.2 | 29/29 | 0 | 0.250 0 | D3S1744 | 14/15 | 14/18 | 1 | 1.640 4 |
| Penta E | 5/23 | 20/23 | 1 | 7.646 4 | D2S441 | 11/12 | 11/11 | 1 | 0.982 3 |
| D10S1248 | 13/13 | 13/15 | 1 | 0.908 6 | D18S535 | 9/13 | 12/13 | 1 | 0.875 9 |
| D8S1179 | 11/14 | 11/11 | 1 | 2.920 9 | D13S325 | 20/23 | 18/20 | 1 | 0.721 5 |
| D1S1656 | 14/16 | 12/16 | 1 | 0.843 3 | D7S1517 | 21/25 | 23/25 | 1 | 0.978 9 |
| D18S51 | 14/17 | 14/16 | 1 | 0.828 7 | D10S1435 | 12/13 | 12/12 | 1 | 0.909 8 |
| D12S391 | 18/21 | 19/21 | 1 | 1.250 0 | D11S2368 | 22/23 | 18/22 | 1 | 1.903 4 |
| D6S1043 | 11/13 | 11/18 | 1 | 1.392 6 | D4S2366 | 9/9 | 13/13 | 0 | 0.250 0 |
| D19S433 | 14/15.2 | 13/14 | 1 | 0.756 3 | D7S3048 | 21/23 | 20/21 | 1 | 1.288 2 |
| D16S539 | 10/11 | 10/11 | 2 | 5.495 4 | D5S2500 | 15/15 | 12/15 | 1 | 1.046 2 |
| D13S317 | 7/8 | 7/11 | 1 | 89.535 7 | |||||
| 高变区 | 姐姐 | 弟弟 |
|---|---|---|
| HVR-Ⅰ(16 166~16 430 nt) | 16189 C | 16189 C |
| 16223 T | 16223 T | |
| 16267 T | 16267 T | |
| 16362 C | 16362 C | |
| 16423 DEL | 16423 DEL | |
| HVR-Ⅱ(66~307 nt) | 73 G | 73 G |
| 150 T | 150 T | |
| 263 G | 263 G |
Tab. 2 Sequencing results of mtDNA HVR-Ⅰ and HVR-Ⅱ
| 高变区 | 姐姐 | 弟弟 |
|---|---|---|
| HVR-Ⅰ(16 166~16 430 nt) | 16189 C | 16189 C |
| 16223 T | 16223 T | |
| 16267 T | 16267 T | |
| 16362 C | 16362 C | |
| 16423 DEL | 16423 DEL | |
| HVR-Ⅱ(66~307 nt) | 73 G | 73 G |
| 150 T | 150 T | |
| 263 G | 263 G |
| 1 | WALSH P S, METZGER D A, HIGUCHI R. Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material[J]. Biotechniques,1991,10(4):506-513. |
| 2 | 中华人民共和国司法部. 生物学全同胞关系鉴定技术规范: [S].2021. |
| Ministry of Justice of the People’s Republic of China. Technical specification for identification of biological full sibling relationship: [S]. 2021. | |
| 3 | 林源,阙庭志,赵珍敏,等. GoldeneyeTM DNA身份鉴定系统22NC试剂盒的法医遗传学调查[J].法医学杂志,2015,31(4):280-283. doi:10.3969/j.issn.1004-5619.2015.04.007 . |
| LIN Y, QUE T Z, ZHAO Z M, et al. Forensic investigation of GoldeneyeTM DNA ID 22NC kit[J]. Fayixue Zazhi,2015,31(4):280-283. | |
| 4 | 包云,盛翔,张家硕,等. SiFaSTRTM 23plex DNA身份鉴定系统在华东汉族人群中的法医学应用[J].法医学杂志,2018,34(2):120-125. doi:10.3969/j.issn.1004- 5619.2018.02.003 . |
| BAO Y, SHENG X, ZHANG J S, et al. Forensic application of SiFaSTRTM 23plex DNA ID system in Han population of eastern China[J]. Fayixue Zazhi,2018,34(2):120-125. | |
| 5 | 陆惠玲,杨庆恩. 用ITO法计算两个体间的血缘关系机会[J].中国法医学杂志,2002,17(3):188-191. doi:10.3969/j.issn.1001-5728.2002.03.039 . |
| LU H L, YANG Q E. Calculating the probability of kinship between two individuals by ITO method[J]. Zhongguo Fayixue Zazhi,2002,17(3):188-191. | |
| 6 | 赵书民,张素华,阙庭志,等. 两个个体间常用亲缘关系指数的统一算法[J].法医学杂志,2011,27(5):330-333. doi:10.3969/j.issn.1004-5619.2011.05.004 . |
| ZHAO S M, ZHANG S H, QUE T Z, et al. Establishment of universal algorithms for commonly used kinship indices between two individuals[J]. Fa-yixue Zazhi,2011,27(5):330-333. | |
| 7 | 台运春,陆惠玲,吕德坚,等. 常染色体STR鉴定同胞的应用探讨[J].中山大学学报(医学科学版),2006,27(3):302-305. doi:10.3321/j.issn:1672-3554.2006.03.015 . |
| TAI Y C, LU H L, LÜ D J, et al. Application of autosomal STR genetic markers in sibling identification[J]. Zhongshan Daxue Xuebao (Medical sciences),2006,27(3):302-305. | |
| 8 | 中华人民共和国司法部司法鉴定管理局. 生物学全同胞关系鉴定实施规范: [S].2014. |
| Judical Expertise Administration, Ministry of Justice of the People’s Republic of China. Code of practice for identification of biological full sibling relationship: [S]. 2014. | |
| 9 | 阙庭志,赵书民,李成涛. 多种遗传标记在同母异父半同胞关系鉴定中的综合应用[J].法医学杂志,2010,26(4):279-281,300. doi:10.3969/j.issn.1004-5619.2010.04.012 . |
| QUE T Z, ZHAO S M, LI C T. Application of multiple polymorphism genetic markers in determination of half sibling sharing a same mother[J]. Fayixue Zazhi,2010,26(4):279-281,300. | |
| 10 | 赵书民,李成涛,张素华,等. 应用常染色体STR基因座共有等位基因数判别全同胞关系[J].法医学杂志,2009,25(4):267-270. doi:10.3969/j.issn.1004-5619.2009.04.008 . |
| ZHAO S M, LI C T, ZHANG S H, et al. Application of the number of allele shared among autosomal STR loci in full sibling identification[J]. Fa-yixue Zazhi,2009,25(4):267-270. | |
| 11 | 林源,朱如心. 多个遗传标记联合用于全同胞姐妹关系鉴定1例[J].中国司法鉴定,2015(1):120-122. doi:10.3969/j.issn.1671-2072.2015.01.027 . |
| LIN Y, ZHU R X. Identification of full sibling sisterhood using multiple genetic markers: A case report[J]. Zhongguo Sifa Jianding,2015(1):120-122. |
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