doi:10.12116/j.issn.1004-5619.2024.340605

Abstract

CLC Number:

Add to citation manager EndNote|Ris|BibTeX

URL: http://www.fyxzz.cn/EN/10.12116/j.issn.1004-5619.2024.340605

http://www.fyxzz.cn/EN/Y2024/V40/I6/525

References 34

1	FDA Foods and Veterinary Medicine Science and Research Steering Committee. Acceptance criteria for confirmation of identity of chemical residues using exact mass data within the Office of Foods and Veterinary Medicine[Z/OL]. （2015-09-24）[2024-05-25]. .
2	HEINSVIG P J， NOBLE C， DALSGAARD P W， et al. Forensic drug screening by liquid chromatography hyphenated with high-resolution mass spectrometry （LC-HRMS）[J]. Trac Trends Anal Chem，2023，162：117023. doi：10.1016/j.trac.2023.117023 .
3	TELVING R， HASSELSTRØM J B， ANDREASEN M F. Targeted toxicological screening for acidic， neutral and basic substances in postmortem and antemortem whole blood using simple protein precipitation and UPLC-HR-TOF-MS[J]. Forensic Sci Int，2016，266：453-461. doi：10.1016/j.forsciint.2016.07.004 .
4	MARGAGLIOTTI G， BOLLÉ T. Machine learning & forensic science[J]. Forensic Sci Int，2019，298：138-139. doi：10.1016/j.forsciint.2019.02.045 .
5	KLINGBERG J， CAWLEY A， SHIMMON R， et al. Towards compound identification of synthetic opioids in nontargeted screening using machine learning tech-niques[J]. Drug Test Anal，2021，13（5）：990-1000. doi：10.1002/dta.2976 .
6	MARDAL M， DALSGAARD P W， RASMUSSEN B S， et al. Scalable analysis of untargeted LC-HRMS data by means of SQL database archiving[J]. Anal Chem，2023，95（10）：4592-4596. doi：10.1021/acs.analchem.2c03769 .
7	United Nations Office on Drugs and Crime. Current NPS threats[R/OL]. （2024-07-15）[2024-05-30]. .
8	SHI Y， LIU M， LI X， et al. Simultaneous screening of 239 synthetic cannabinoids and metabolites in blood and urine samples using liquid chromatography-high resolution mass spectrometry[J]. J Chromatogr A，2022，1663：462743. doi：10.1016/j.chroma.2021.462743 .
9	MARCHEI E， FERRI M A， TORRENS M， et al. Ultra-high performance liquid chromatography-high resolution mass spectrometry and high-sensitivity gas chromatography-mass spectrometry screening of classic drugs and new psychoactive substances and metabolites in urine of consumers[J]. Int J Mol Sci，2021，22（8）：4000. doi：10.3390/ijms22084000 .
10	HUANG Y， JIA W， CHEN Y， et al. A comprehensive analytical strategy based on characteristic fragments to detect synthetic cannabinoid analogs in seized products and hair samples[J]. Talanta，2023，265：124830. doi：10.1016/j.talanta.2023.124830 .
11	赵苑余，陈江，温晓静，等. 高分辨质谱法快速测定芬太尼类物质及其质谱裂解规律[J].刑事技术，2022，47（2）：111-120. doi：10.16467/j.1008-3650.2021.0112 .
	ZHAO Y Y， CHEN J， WEN X J， et al. Rapid determination of fentanyl-kind analogs and their mass fragmentation routes by high resolution mass spectrometry[J]. Xingshi Jishu，2022，47（2）：111-120.
12	MAJEED H A， BOS T S， VOETEN R L C， et al. Trapped ion mobility mass spectrometry of new psychoactive substances： Isomer-specific identification of ring-substituted cathinones[J]. Anal Chim Acta，2023，1264：341276. doi：10.1016/j.aca.2023.341276 .
13	BADE R， VAN HERWERDEN D， ROUSIS N， et al. Workflow to facilitate the detection of new psychoactive substances and drugs of abuse in influent urban wastewater[J]. J Hazard Mater，2024，469：133955. doi：10.1016/j.jhazmat.2024.133955 .
14	SALGUEIRO-GONZÁLEZ N， CASTIGLIONI S， GRACIA-LOR E， et al. Flexible high resolution-mass spectrometry approach for screening new psychoactive substances in urban wastewater[J]. Sci Total Environ，2019，689：679-690. doi：10.1016/j.scito tenv.2019.06.336 .
15	NIELSEN K L， TELVING R， ANDREASEN M F， et al. A metabolomics study of retrospective forensic data from whole blood samples of humans exposed to 3，4-methylenedioxymethamphetamine： A new approach for identifying drug metabolites and changes in metabolism related to drug consumption[J]. J Proteome Res，2016，15（2）：619-627. doi：10.1021/acs.jproteome.5b01023 .
16	WANG T， NIELSEN K L， FRISCH K， et al. A retrospective metabolomics analysis of gamma-hydroxybutyrate in humans： New potential markers and changes in metabolism related to GHB consumption[J]. Front Pharmacol，2022，13：816376. doi：10.3389/fphar.2022.816376 .
17	刘文乔，白锐，马春玲，等. 丁卡因急性中毒致死小鼠血清和组织的代谢组学变化[J].法医学杂志，2021，37（2）：166-174. doi：10.12116/j.issn.1004-5619.2020.401006 .
	LIU W Q， BAI R， MA C L， et al. Metabolomics changes of serum and tissues in mice died of acute tetracaine poisoning[J]. Fayixue Zazhi，2021，37（2）：166-174.
18	ELMSJÖ A， SÖDERBERG C， JAKOBSSON G， et al. Postmortem metabolomics reveal acylcarnitines as potential biomarkers for fatal oxycodone-related intoxication[J]. Metabolites，2022，12（2）：109. doi：10.3390/metabo12020109 .
19	LOPES R P， FERRO R A， MILHAZES M， et al. Metabolic stability and metabolite profiling of emerging synthetic cathinones[J]. Front Pharmacol，2023，14：1145140. doi：10.3389/fphar.2023.1145140 .
20	PELLETIER R， BOURDAIS A， FABRESSE N， et al. In silico and in vitro metabolism studies of the new synthetic opiate AP-237 （bucinnazine） using bioinformatics tools[J]. Arch Toxicol，2024，98（1）：165-179. doi：10.1007/s00204-023-03617-x .
21	BERARDINELLI D， TAOUSSI O， CARLIER J， et al. In vitro， in vivo metabolism and quantification of the novel synthetic opioid N-piperidinyl etonitazene （etonitazepipne）[J]. Clin Chem Lab Med，2024，62（8）：1580-1590. doi：10.1515/cclm-2023-1360 .
22	XU L， LIU X， SONG Z， et al. In vitro and in vivo metabolism of 3-methoxyeticyclidine in human liver microsomes， a zebrafish model， and two human urine samples based on liquid chromatography-high-resolution mass spectrometry[J]. Drug Test Anal，2024，16（1）：30-37. doi：10.1002/dta.3488 .
23	XU L， YAN H， TANG Y， et al. In vitro and in vivo metabolic study of three new psychoactive β-keto-arylcyclohexylamines[J]. J Anal Toxicol，2024，48（4）：217-225. doi：10.1093/jat/bkae020 .
24	LIU X， TANG Y， XU L， et al. Metabolism of ADB-FUBIATA in zebrafish and pooled human liver microsomes investigated by liquid chromatography-high-resolution mass spectrometry[J]. Rapid Commun Mass Spectrom，2024，38（9）：e9730. doi：10.1002/rcm.9730 .
25	TANG Y， XU L， ZHAO J， et al. Metabolism of dipentylone in zebrafish and human liver microsomes determined by liquid chromatography-high resolution mass spectrometry[J]. J Pharm Biomed Anal，2023，236：115710. doi：10.1016/j.jpba.2023.115710 .
26	CUI X， LIAN R， CHEN J， et al. Source identification of heroin by rapid detection of organic impurities using direct analysis in real time with high-resolution mass spectrometry and multivariate statistical analysis[J]. Microchem J，2019，147：121-126. doi：10.1016/j.microc.2019.03.014 .
27	LIANG L， LI C， FANG J， et al. An integrated screening method for paralytic shellfish toxins and their analogues based on fragmentation characteristics using an orbitrap-based ultrahigh-performance liquid chromatography-high-resolution mass spectrometry[J]. Food Chem，2024，434：137502. doi：10. 1016/j.foodchem.2023.137502 .
28	LI Z， HUANG X， WANG X， et al. Establishment and application of a screening method for 354 organic toxicants in blood and urine with high-performance liquid chromatography-high-resolution orbitrap mass spectrometry[J]. Anal Bioanal Chem，2023，415（3）：493-507. doi：10.1007/s00216-022-04432-6 .
29	AYALA J， KERRIGAN S. Comprehensive toxicological screening of common drugs of abuse， new psychoactive substances and cannabinoids in blood using supported liquid extraction and liquid chromatography-quadrupole time-of-flight mass spectrometry[J]. J Anal Toxicol，2023，47（8）：656-667. doi：10.1093/jat/bkad069 .
30	MASSANO M， INCARDONA C， GERACE E， et al. Development and validation of a UHPLC-HRMS-QTOF method for the detection of 132 new psychoactive substances and synthetic opioids， including fentanyl， in dried blood spots[J]. Talanta，2022，241：123265. doi：10.1016/j.talanta.2022.123265 .
31	JOYE T， SIDIBÉ J， DÉGLON J， et al. Liquid chromatography-high resolution mass spectrometry for broad-spectrum drug screening of dried blood spot as microsampling procedure[J]. Anal Chim Acta，2019，1063：110-116. doi：10.1016/j.aca.2019.02.011 .
32	HOUZÉ P， BOROWSKI I， BITO E， et al. New trend in toxicological screening using volumetric absorptive microsampling （VAMS） and high-resolution mass spectrometry （HR/MS） combination[J]. Molecules， 2023，28（8）：3466. doi：10.3390/molecules28083466 .
33	XU J， ZHANG Z， LIU R， et al. Function of complement factor H and imaging of small molecules by MALDI-MSI in a methamphetamine behavioral sensitization model[J]. Behav Brain Res，2019，364：233-244. doi：10.1016/j.bbr.2019.02.002 .
34	LIN J， YANG S， JI J， et al. Natural or artificial： An example of topographic spatial distribution analysis of mescaline in cactus plants by matrix-assisted laser desorption/ionization mass spectrometry imaging[J]. Front Plant Sci，2023，14：1066595. doi：10.3389/fpls.2023.1066595 .

[1]	Xin-ying WANG, Jia-li ZHANG, Ping XIANG, Xin WANG. Research Progress on Hair Metabolomics and Its Application in Forensic Science [J]. Journal of Forensic Medicine, 2026, 42(1): 49-55.
[2]	Jie YANG, Yi-lei HU, Jin-ming WANG, Zheng-dong LI. Analysis of the Injury Mechanism of Traumatic Craniocerebral Injury from Falls Based on Finite Element Simulation [J]. Journal of Forensic Medicine, 2026, 42(1): 1-7.
[3]	Run-ting DOU, Shun CHENG, Xin ZHOU, Xing YE, Zhi-min WANG, Guang-hui HONG, Qi ZHANG, Qing XIA, Yi-wen SHEN. Machine Learning Model Based on Structured Injury Features for Knee Mobility Discriminations after Traumatic Injury [J]. Journal of Forensic Medicine, 2026, 42(1): 8-16.
[4]	Tian WANG, Li-wei ZHANG, Dai-jing YU, Jun ZHANG, Jiang-wei YAN. Visual Analysis of the Current Status and Trends in Forensic Microbiology Research Based on Bibliometrics [J]. Journal of Forensic Medicine, 2026, 42(1): 17-25.
[5]	Yi-hua SUN, Jian CHEN, Yong-sheng LI. Comparison of the Forensic Testing Performance of Six STR Kits [J]. Journal of Forensic Medicine, 2026, 42(1): 26-33.
[6]	Qiong JIA, Kai-jun JIN, Shi-qi LIU, Yi-meng ZHANG, Yun-le MENG, Hao NIE, Sheng HU, Fan YANG, Xing-chun ZHAO, Jian YE. Research Progress on the Methodological System for Decomposition Stage Classification in Forensic Medicine [J]. Journal of Forensic Medicine, 2026, 42(1): 34-42.
[7]	Xin NIU, Zhe CAO. Forensic Significance of Mesenteric Injury in Child Abuse Cases [J]. Journal of Forensic Medicine, 2026, 42(1): 43-48.
[8]	Xiao-tian YU, Sheng-nan WU, Wen-ting WANG, Yuan-yuan LIU, Ning-guo LIU. Forty Years of Dedicated Development： Establishing a High-Quality Academic Platform for Forensic Medicine — A Review of the 40-Year History of Fayixue Zazhi [J]. Journal of Forensic Medicine, 2026, 42(1): 56-63.
[9]	Hang CHEN. Letter to the Editor： On Critical Toxicological Information of Newly Discovered Toxic Substances and Illegal Drugs [J]. Journal of Forensic Medicine, 2026, 42(1): 64-65.
[10]	Hang CHEN, Xin WANG, Hui YAN, Ping XIANG. Synthetic Drug： Pregabalin [J]. Journal of Forensic Medicine, 2026, 42(1): 66-68.
[11]	Zhen WANG, Tai-qi ZANG. Comprehensive Identification of the Vulnerant by Examining Marks on Clothing and Bodies Combining with Trace Comparison： A Case Report [J]. Journal of Forensic Medicine, 2026, 42(1): 69-72.
[12]	Jia MENG, Ling-yu LI, Wu-lin HUANG, Tong ZHOU, Meng-qin ZOU, Jian-wei PENG, Bo LI, Xin HUANG, Qing-bo ZHANG. Multidisciplinary Identification in a Hit-and-Run Traffic Accident： A Case Report [J]. Journal of Forensic Medicine, 2026, 42(1): 73-76.
[13]	Cong-da SHEN, Shi-fan WU, Yi WU, Wen-dong MAO, Xiang-tao MA. Fatal Rupture of the Abdominal Aorta Caused by Trampling： A Case Report [J]. Journal of Forensic Medicine, 2026, 42(1): 77-78.
[14]	Jun-jiang CHEN, Lan-jiang LI, Pu-ping LEI, Shang-wen WANG, Xin-biao LIAO, Li-fang CHEN, Huan ZHANG. Forensic Identification of a Fatality from Confined Container Deflagration Complicated by Tertiary Blast Injury： A Case Report [J]. Journal of Forensic Medicine, 2026, 42(1): 79-83.
[15]	Jian YE, Yong-liang HU, Ya-ling XIE, Yu CAI, Wen-hao LI. Medical Damage Identification of CT Guided Pulmonary Nodule Localization Needle Escapes to the Left Ventricle： A Case Report [J]. Journal of Forensic Medicine, 2026, 42(1): 83-86.

RichHTML

PDF (PC)

Supplement

Knowledge

Abstract

Cite this article

share this article

References 34

Related Articles 15

Recommended Articles

Metrics