Journal of Forensic Medicine ›› 2025, Vol. 41 ›› Issue (4): 404-406.DOI: 10.12116/j.issn.1004-5619.2023.530705
• Case Reports • Previous Articles
Received:2023-07-06
Online:2025-11-25
Published:2025-08-25
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URL: http://www.fyxzz.cn/EN/10.12116/j.issn.1004-5619.2023.530705
| 基因座 | 张某甲 | 张某乙 | FSI | IBS | 基因座 | 张某甲 | 张某乙 | FSI | IBS |
|---|---|---|---|---|---|---|---|---|---|
| D6S477 | 13，17 | 15，16 | 0.250 | 0 | D19S433 | 13，15.2 | 13，14 | 0.718 | 1 |
| D18S535 | 9，13 | 9，10 | 0.910 | 1 | D5S818 | 10，13 | 10，12 | 0.801 | 1 |
| D19S253 | 7 | 7 | 11.154 | 2 | D21S11 | 29，33.2 | 32，33.2 | 3.832 | 1 |
| D15S659 | 12，13 | 12，14 | 0.824 | 1 | D18S51 | 13，16 | 13，21 | 1.470 | 1 |
| D11S2368 | 18，21 | 21，24 | 0.874 | 1 | D6S1043 | 19，20 | 19，20 | 3.233 | 2 |
| D20S470 | 16，17 | 16，17 | 2.490 | 2 | D3S1358 | 15，16 | 15，16 | 0.957 | 2 |
| D1S1656 | 12，16 | 12，16 | 3.556 | 2 | D13S317 | 8，11 | 11 | 1.300 | 1 |
| D22-GATA198B05 | 21，23 | 17，21 | 0.649 | 1 | D7S820 | 10 | 11，12 | 0.250 | 0 |
| D16S539 | 11 | 11 | 5.941 | 2 | D2S441 | 12 | 12 | 11.986 | 2 |
| D7S3048 | 20，26 | 20，26 | 6.900 | 2 | CSF1PO | 12 | 12 | 3.981 | 2 |
| D8S1132 | 20，21 | 20，21 | 2.066 | 2 | Penta D | 11，12 | 12 | 1.657 | 1 |
| D4S2366 | 9，12 | 12，13 | 1.000 | 1 | vWA | 16，18 | 14，16 | 1.063 | 1 |
| D21S1270 | 10，12.3 | 10 | 1.048 | 1 | D8S1179 | 11，16 | 11 | 4.015 | 1 |
| D13S325 | 22 | 22 | 117.361 | 2 | TPOX | 8，11 | 8，11 | 12.450 | 2 |
| D9S925 | 16 | 16 | 4.669 | 2 | Penta E | 12，16 | 12，16 | 2.703 | 2 |
| D3S3045 | 9，12 | 9 | 1.048 | 1 | THO1 | 6 | 6，7 | 2.793 | 1 |
| D14S608 | 9 | 7，9 | 2.074 | 1 | D12S391 | 19 | 19，23 | 1.266 | 1 |
| D10S1435 | 11，14 | 8，14 | 1.103 | 1 | D2S1338 | 19，23 | 20，23 | 0.824 | 1 |
| D17S1290 | 11，15 | 11，15 | 3.807 | 2 | FGA | 24，25 | 24，25 | 3.259 | 2 |
| D5S2500 | 11，15 | 11 | 1.084 | 1 |
Tab. 1 Genotyping results of 39 autosomal STR loci for ZHANG A and ZHANG B
| 基因座 | 张某甲 | 张某乙 | FSI | IBS | 基因座 | 张某甲 | 张某乙 | FSI | IBS |
|---|---|---|---|---|---|---|---|---|---|
| D6S477 | 13，17 | 15，16 | 0.250 | 0 | D19S433 | 13，15.2 | 13，14 | 0.718 | 1 |
| D18S535 | 9，13 | 9，10 | 0.910 | 1 | D5S818 | 10，13 | 10，12 | 0.801 | 1 |
| D19S253 | 7 | 7 | 11.154 | 2 | D21S11 | 29，33.2 | 32，33.2 | 3.832 | 1 |
| D15S659 | 12，13 | 12，14 | 0.824 | 1 | D18S51 | 13，16 | 13，21 | 1.470 | 1 |
| D11S2368 | 18，21 | 21，24 | 0.874 | 1 | D6S1043 | 19，20 | 19，20 | 3.233 | 2 |
| D20S470 | 16，17 | 16，17 | 2.490 | 2 | D3S1358 | 15，16 | 15，16 | 0.957 | 2 |
| D1S1656 | 12，16 | 12，16 | 3.556 | 2 | D13S317 | 8，11 | 11 | 1.300 | 1 |
| D22-GATA198B05 | 21，23 | 17，21 | 0.649 | 1 | D7S820 | 10 | 11，12 | 0.250 | 0 |
| D16S539 | 11 | 11 | 5.941 | 2 | D2S441 | 12 | 12 | 11.986 | 2 |
| D7S3048 | 20，26 | 20，26 | 6.900 | 2 | CSF1PO | 12 | 12 | 3.981 | 2 |
| D8S1132 | 20，21 | 20，21 | 2.066 | 2 | Penta D | 11，12 | 12 | 1.657 | 1 |
| D4S2366 | 9，12 | 12，13 | 1.000 | 1 | vWA | 16，18 | 14，16 | 1.063 | 1 |
| D21S1270 | 10，12.3 | 10 | 1.048 | 1 | D8S1179 | 11，16 | 11 | 4.015 | 1 |
| D13S325 | 22 | 22 | 117.361 | 2 | TPOX | 8，11 | 8，11 | 12.450 | 2 |
| D9S925 | 16 | 16 | 4.669 | 2 | Penta E | 12，16 | 12，16 | 2.703 | 2 |
| D3S3045 | 9，12 | 9 | 1.048 | 1 | THO1 | 6 | 6，7 | 2.793 | 1 |
| D14S608 | 9 | 7，9 | 2.074 | 1 | D12S391 | 19 | 19，23 | 1.266 | 1 |
| D10S1435 | 11，14 | 8，14 | 1.103 | 1 | D2S1338 | 19，23 | 20，23 | 0.824 | 1 |
| D17S1290 | 11，15 | 11，15 | 3.807 | 2 | FGA | 24，25 | 24，25 | 3.259 | 2 |
| D5S2500 | 11，15 | 11 | 1.084 | 1 |
| 基因座 | 张某甲 | 张某乙 | 基因座 | 张某甲 | 张某乙 | 基因座 | 张某甲 | 张某乙 |
|---|---|---|---|---|---|---|---|---|
| DYS391 | 10 | 10 | Y-GATA-H4 | 10 | 11 | DYS481 | 24 | 24 |
| DYS389Ⅰ | - | 13 | DYS447 | - | 26 | DYF387S1 | - | 37，38 |
| DYS439 | - | 11 | DYS19 | 16 | 16 | DYS533 | - | 13 |
| DYS389Ⅱ | - | 29 | DYS392 | - | 11 | DYS518 | - | 37 |
| DYS438 | - | 10 | DYS393 | 15 | 14 | DYS570 | 16 | 16 |
| DYS456 | 15 | 15 | DYS390 | - | 23 | DYS449 | 30 | 30 |
| DYS458 | 16 | 16 | DYS385a/b | - | 12，18 | DYS527a/b | 19，21 | 19，21 |
| DYS437 | - | 14 | DYS576 | 20 | 20 | DYS522 | 11 | 11 |
| DYS635 | - | 21 | DYS627 | 18 | 18 | DYS388 | - | 13 |
| DYS448 | - | 21 | DYS460 | - | 11 | DYS444 | - | 13 |
Tab. 2 Genotyping results of 33 Y-STR loci for ZHANG A and ZHANG B
| 基因座 | 张某甲 | 张某乙 | 基因座 | 张某甲 | 张某乙 | 基因座 | 张某甲 | 张某乙 |
|---|---|---|---|---|---|---|---|---|
| DYS391 | 10 | 10 | Y-GATA-H4 | 10 | 11 | DYS481 | 24 | 24 |
| DYS389Ⅰ | - | 13 | DYS447 | - | 26 | DYF387S1 | - | 37，38 |
| DYS439 | - | 11 | DYS19 | 16 | 16 | DYS533 | - | 13 |
| DYS389Ⅱ | - | 29 | DYS392 | - | 11 | DYS518 | - | 37 |
| DYS438 | - | 10 | DYS393 | 15 | 14 | DYS570 | 16 | 16 |
| DYS456 | 15 | 15 | DYS390 | - | 23 | DYS449 | 30 | 30 |
| DYS458 | 16 | 16 | DYS385a/b | - | 12，18 | DYS527a/b | 19，21 | 19，21 |
| DYS437 | - | 14 | DYS576 | 20 | 20 | DYS522 | 11 | 11 |
| DYS635 | - | 21 | DYS627 | 18 | 18 | DYS388 | - | 13 |
| DYS448 | - | 21 | DYS460 | - | 11 | DYS444 | - | 13 |
Fig. 1 Y chromosome microdeletion genotyping profiles of ZHANG A and ZHANG B
| [1] | 中华人民共和国司法部. 生物学全同胞关系鉴定技术规范： [S].北京：中国标准出版社，2021. |
| Ministry of Justice of the People’s Republic of China. Technical specification for identification of biological full sibling relationship： [S]. Beijing： Standards Press of China，2021. | |
| [2] | KRAUSZ C， HOEFSLOOT L， SIMONI M， et al. EAA/EMQN best practice guidelines for molecular diagnosis of Y-chromosomal microdeletions： State-of-the-art 2013[J]. Andrology，2014，2（1）：5-19. doi：10 . |
| 1111/j.2047-2927.2013.00173.x. | |
| [3] | 史绍杏，马伟，朱传红. Y-STR家系分型及ITO分析法侦破强奸杀人案1例[J].刑事技术，2005（4）：58-59. |
| SHI S X， MA W， ZHU C H. Application of Y-STR pedigree typing and ITO analysis in solving a rape-murder case[J]. Xingshi Jishu，2005（4）：58-59. | |
| [4] | ZHU X B， LIU Y L， ZHANG W， et al. Vertical transmission of the Yq AZFc microdeletion from father to son over two or three generations in infertile Han Chinese families[J]. Asian J Androl，2010，12（2）：240-246. doi：10.1038/aja.2009.63 . |
| [5] | CHANG P L， SAUER M V， BROWN S. Y chromosome microdeletion in a father and his four infertile sons[J]. Hum Reprod，1999，14（11）：2689-2694. doi：10.1093/humrep/14.11.2689 . |
| [6] | 刘睿智. 无精子症因子缺失与男性不育相关性研究进展[J].中华男科学杂志，2012，18（11）：963-968. doi：10.13263/j.cnki.nja.2012.11.012 . |
| LIU R Z. AZF deletions and male infertility[J]. Zhonghua Nankexue Zazhi，2012，18（11）：963-968. | |
| [7] | 王燕超，马晓燕，孙筱放，等. Y染色体微缺失人群中Y-STR等位基因缺失模式分析[J].遗传，2019，41（3）：243-253. doi：10.16288/j.yczz.18-235 . |
| WANG Y C， MA X Y， SUN X F， et al. Alleles dropout patterns of Y-short tandem repeats in infertile males with Y chromosome microdeletions[J]. Yi-chuan，2019，41（3）：243-253. |
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