法医学杂志 ›› 2023, Vol. 39 ›› Issue (2): 168-175.DOI: 10.12116/j.issn.1004-5619.2022.320202
收稿日期:
2022-02-21
发布日期:
2023-06-06
出版日期:
2023-04-25
通讯作者:
徐兴敏,莫耀南
作者简介:
程忠平(1979—),男,硕士研究生,主要从事法医病理学和法医毒物学研究;E-mail:czp159777@qq.com
基金资助:
Zhong-ping CHENG(), Yan-fei LIU, Xing-min XU(
), Yao-nan MO(
)
Received:
2022-02-21
Online:
2023-06-06
Published:
2023-04-25
Contact:
Xing-min XU, Yao-nan MO
摘要:
鉴于法医学痕量分析中生物样本的复杂性以及目标物的痕量性,需要一种简单有效的方法从复杂基质中获得足量的目标物。磁性纳米颗粒(magnetic nanoparticle,MNP)凭借其独特的超顺磁性、稳定的物理化学性质、生物相容性、尺寸小、较高的比表面积等特性,已在生物医药、药物递送和药物分离等多个研究领域显现出广泛的应用价值。为了将MNP应用于法医检材的前处理,最大程度地增加目标物的提取率,尽可能减少干扰因素以满足目标物痕量分析要求,本文综述了近年来MNP在法医毒物分析、环境法医学、痕量物证分析和刑事侦查领域的应用进展,为MNP在法医学痕量分析中的应用提供研究思路。
中图分类号:
程忠平, 刘燕飞, 徐兴敏, 莫耀南. 磁性纳米颗粒在法医学痕量分析中的应用进展[J]. 法医学杂志, 2023, 39(2): 168-175.
Zhong-ping CHENG, Yan-fei LIU, Xing-min XU, Yao-nan MO. Progress in the Application of Magnetic Nanoparticles in Forensic Trace Analysis[J]. Journal of Forensic Medicine, 2023, 39(2): 168-175.
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