法医学杂志

法医学杂志 ›› 1992, Vol. 8 ›› Issue (1): 1-8+48.

• 论文 •    下一篇

负离子质谱法在毒物分析中的应用

沈敏;孙亚娟;   

  1. 司法部司法鉴定科学技术研究所,司法部司法鉴定科学技术研究所 上海 200063,上海 200063
  • 发布日期:1992-02-25 出版日期:1992-02-28

APPLICATION OF NEGATIVE ION CHEMICAL IONIZATION MASS SPECTROMETRY IN FORENSIC ANALYTICAL TOXICOLOGY

SHEN MIN, SUN YAJUAN. INSTITUTE OF FORENSIC SCIENCES, MINISTRY OF JUSTICE, PRC; SHANGHAI, CHINA 200063   

  • Online:1992-02-25 Published:1992-02-28

被引次数

4

摘要： 本文应用负离子质谱法系统分析了有机磷类,拟除虫菊酯类,氨基甲酸酯类杀虫剂,巴比妥类,苯二氮?类、吩噻嗪类,生物碱类药物及其它常见的毒物.结果表明负离子质谱因具有质谱图简单,结构特征显著,灵敏度高,杂质干扰少等优点而成为未知毒物鉴定的有用工具.

关键词: 质谱, 负离子质谱, 毒(药)物, 杀虫剂

Abstract: The successful application of the GC/NICIMS technique for the analysis of abuse drugs and pesticides are presented, including organophosphorus, carbamate, pyrethroid, phenothiazine, barbiturates, benzodiaepines, alkaloids and other toxic substances. This study demonstrated that negative CI mass spectrometry may become a valuable tool, specially using negative CI in combination with positive CI and EI in the identification of unknown compound, because it has advantages of simple mass spectrum, obvious structrural information, high sensitivity and very few interference.