法医学杂志

法医学杂志 ›› 2006, Vol. 22 ›› Issue (3): 217-219.

• 论文 • 上一篇    下一篇

乙酰甲胺磷中毒血液灌流血药浓度的动态检测

褚建新;沈驹华;蒋文慧;   

  1. 浙江省人民检察院,德清县人民医院,杭州市人民检察院 浙江杭州310012,浙江德清313216,浙江杭州310014
  • 发布日期:2006-06-25 出版日期:2006-06-28

Dynamic Determination of the Medicine Concentration of Poisoned Blood of Acephate

CHU JIAN-XIN1, SHEN JU-HUA2, JIANG WEN-HUI3(1.THE PEOPLE′S PROCURATORATE OF ZHEJIANG PROVINCE, HANGZHOU 310012, CHINA; 2.THE PEOPLE′S HOSPITAL OF DEQING,DEQING 313216, CHINA; 3.THE PEOPLE′S PROCURATORATE OF HANGZHOU, HANGZHOU 310014, CHINA)   

  • Online:2006-06-25 Published:2006-06-28

被引次数

11

摘要： 目的探索乙酰甲胺磷中毒在血液灌流(HP)过程中血药浓度的变化规律及终末浓度。方法采用医院急诊病例病人股静脉血,通过气相色谱法分析血浆中的乙酰甲胺磷含量。结果经血液灌流后血浆中乙酰甲胺磷浓度迅速下降,并呈现出灌流前血药浓度越高下降速度越快的特性。结论血液灌流法能迅速降低血液中乙酰甲胺磷浓度,其下降的速度受制于乙酰甲胺磷的初始浓度和灌流开始时间等。

关键词: 乙酰甲胺磷, 中毒, 血药浓度, 血液灌流, GC

Abstract: Objective To observe rule of medicine concentration of blood and the last concentration that through hemoperfusion after poisoned by acephate. Methods Utilizeng the patient annual bonus venous blood in hospital emergency room, the content of acephate in plasma was analyzed by gas chromatography. Results After hemoperfusion, the concentration of acephate showed a rapid drop and the characteristic that the concentration drops quicker if medicine concentration of blood before hemoperfusion is higher. Conclusion Hemoperfusion is able to rapidly reduce the concentration of acephate in blood, its speed is determined by initial concentration and the beginning time of hemoperfusion etc.

Key words: poisoning, hydropneumatic pouring, GC