法医学杂志

法医学杂志 ›› 2005, Vol. 0 ›› Issue (1): 65-67.

• 论文 • 上一篇    下一篇

Rh血型系统的分子生物学研究进展

孙志刚,丁梅,王保捷   

  1. 中国医科大学法医学院,中国医科大学法医学院,中国医科大学法医学院 辽宁沈阳110001 ,辽宁沈阳110001 ,辽宁沈阳110001
  • 发布日期:2005-02-25 出版日期:2005-02-28

Molecular Biology Advance in the Rh Blood Group System

SUN ZHI-GANG,DING MEI,WANG BAO-JIE (SCHOOL OF FORENSIC MEDICINE, CHINA MEDICAL UNIVERSITY, SHENYANG 110001,CHINA)   

  • Online:2005-02-25 Published:2005-02-28

被引次数

10

摘要： Rh血型是极复杂的人类红细胞血型系统之一,至少包括45种独立的血型抗原。过去的10年间,Rh血型的研究取得了极大的进展,得到了大量分子生物学的研究资料,如Rh血型的遗传方式、RH基因及其进化过程、Rh复合体的结构与功能、红细胞外Rh相似蛋白的表达,Rh基因分型技术也进一步得到发展与改进。本文综述了Rh血型分子生物学的研究进展,以服务于法医学实践。

关键词: Rh血型系统, 分子生物学, 法医学

Abstract: The Rh blood group system is one of the most complex of the known human blood group polymorphisms, including above 45 blood group antigens. Considerable progress has been made in our understanding of the molecular basis of Rh in the past 10 years. The bases of Rh inheritance, RH gene and its evolution, the structure and function of Rh complex, as well as nonerythroid Rh homolog, have been determined. Further improvements have been made in the technology of Rh genotyping. The review provides an update on the advance of Rh blood group to give information in the practice of forensic science.

Key words: Rh blood group system, molecular biology, forensic science