Abstract: Objective To explore the relevance between writing characteristic and therapeutic effect in schizophrenia and to discuss the influence of aggressive behavior on writing characteristic. Methods Recoding the casual and fixed writing in admission, one week, two weeks, four weeks, eight weeks after treatment and rating Positive and Negative Syndrome Scale（PANSS） and Modified Overt Aggression Scale （MOAS）. Choosing two characteristics, “relationship between font and grid lines” and “having big strokes or not”, and comparing before and after treatment. Results Eight weeks after treatment, the score of PANSS decreased. The condition of patients and the writing characteristic improved as well. The differences of writing characteristics were statistically significant in patients with aggressive behavior before and after treatment （P<0.05）. Conclusion The writing characteristic has relation with therapeutic effects and improved with therapeutic effects in aggressive patients.

Key words: forensic psychiatry, schizophrenia, handwriting, therapeutic effect