Abstract: Objective The sensitivity of heart-type fatty acid binding-protein(H-FABP)in the postmortem diagnosis of myocardial ischemia was explored.Methods The changes of H-FABP staining in normal,in - farcted and suspected ischemia of myocardial cells were studied by immunohistochemistry.Results There was no depletion in normal control group,and obvious depletion was observed in myocardial infarcted group.Among9suspected myocardial ischemia group,3cases showed obvious depletion and3cases showed vague depletion for H-FABP,there were obvious depletion of Mb in4suspected myocardial is - chemia cases and vague depletion in2cases for Mb.It is indicated that H-FABP can be used to diag - nose early myocardial ischemia.Conclusion H-FABP is quite sensitive and useful for the diagnosis of early myocardial ischemia.

Key words: early myocardial ischemia, heart-type fatty acid binding-protein(H-FABP), immunohistochem - istry(IHC), myoglobin(Mb)