›› 2004, Vol. 0 ›› Issue (2): 120-123.

• 论文 • Previous Articles     Next Articles

Progress and prospects of HLA genotyping technology

LI CHENG-TAO (INSTITUTE OF FORENSIC SCIENCES, MINISTRY OF JUSTICE, P.R.CHINA, SHANGHAI 200063, CHINA)   

  • Online:2004-04-25 Published:2004-04-28

Abstract: Over a long period of time, studies on HLA structure and function have been the research hotspots. for it is very important to understand the essential of life science and disease mechanism. With the rapid development of molecular biology, HLA typing makes great progress. It has changed from traditional serological typing to DNA-based typing. More and more HLA genotyping methods have been developed and applied. In this essay, the author reviewed and appraised all kinds of HLA genotyping tech niques and introduced two new techniques.

Key words: human leucocyte antigen, genotyping, standardized DNA-based typing