Journal of Forensic Medicine ›› 2025, Vol. 41 ›› Issue (6): 612-615.DOI: 10.12116/j.issn.1004-5619.2024.540802
• Case Reports • Previous Articles Next Articles
Received:2024-08-26
Online:2026-02-27
Published:2025-12-25
CLC Number:
Add to citation manager EndNote|Ris|BibTeX
URL: http://www.fyxzz.cn/EN/10.12116/j.issn.1004-5619.2024.540802
| 基因座 | 流产组织 | 邢某 | 胎儿(推测) | 方某 | 吴某 |
|---|---|---|---|---|---|
| D3S1358 | 16,17 | 16,17 | 16 | 14,17 | 15,16 |
| vWA | 15,16 | 15,16 | 15 | 14,17 | 15,19 |
| D16S539 | 9,11,12 | 9,11 | 9,12 | 9,13 | 11,12 |
| CSF1PO | 8,12,13 | 8,12 | 8,13 | 10,11 | 11,13 |
| D6S1043 | 12,14 | 12 | 12,14 | 13,17 | 14 |
| D8S1179 | 10,12,14 | 10,14 | 10,12 | 12,16 | 12,14 |
| D21S11 | 30,31.2 | 30 | 30,31.2 | 32.2 | 31.2,33.2 |
| D18S51 | 13,16 | 13,16 | 13,16 | 14 | 13,15 |
| D5S818 | 9,12,13 | 9,13 | 9,12 | 11,13 | 12 |
| D2S441 | 11,13,14 | 11,13 | 11,14 | 11,11.3 | 12,14 |
| D19S433 | 13,14 | 13,14 | 13,14 | 12,14 | 13 |
| FGA | 23 | 23 | 23 | 19,23.2 | 22,23 |
| D10S1248 | 13,17 | 13,17 | 13,17 | 14,15 | 15,17 |
| D22S1045 | 11,15 | 15 | 11,15 | 17 | 11,15 |
| D1S1656 | 15,16,17 | 16,17 | 15,17 | 16 | 15 |
| D13S317 | 8,9,11 | 8,9 | 9,11 | 9,11 | 8,11 |
| D7S820 | 8,11 | 11 | 8,11 | 8,11 | 8,11 |
| Penta E | 14,15,21 | 14,15 | 15,21 | 11,14 | 13,21 |
| Penta D | 9,11,13 | 9,11 | 11,13 | 12,13 | 12,13 |
| TH01 | 7,9 | 7,9 | 9 | 6 | 7,9 |
| D12S391 | 17,19,24 | 19,24 | 17,24 | 19 | 17,18 |
| D2S1338 | 21,23,25 | 21,23 | 21,25 | 18,19 | 20,25 |
| TPOX | 8,11 | 8,11 | 8 | 8,9 | 8 |
| Amelogenin | X,Y | X | X,Y | X,Y | X,Y |
Tab. 1 Inferred fetal genotyping and the suspects’ genotyping
| 基因座 | 流产组织 | 邢某 | 胎儿(推测) | 方某 | 吴某 |
|---|---|---|---|---|---|
| D3S1358 | 16,17 | 16,17 | 16 | 14,17 | 15,16 |
| vWA | 15,16 | 15,16 | 15 | 14,17 | 15,19 |
| D16S539 | 9,11,12 | 9,11 | 9,12 | 9,13 | 11,12 |
| CSF1PO | 8,12,13 | 8,12 | 8,13 | 10,11 | 11,13 |
| D6S1043 | 12,14 | 12 | 12,14 | 13,17 | 14 |
| D8S1179 | 10,12,14 | 10,14 | 10,12 | 12,16 | 12,14 |
| D21S11 | 30,31.2 | 30 | 30,31.2 | 32.2 | 31.2,33.2 |
| D18S51 | 13,16 | 13,16 | 13,16 | 14 | 13,15 |
| D5S818 | 9,12,13 | 9,13 | 9,12 | 11,13 | 12 |
| D2S441 | 11,13,14 | 11,13 | 11,14 | 11,11.3 | 12,14 |
| D19S433 | 13,14 | 13,14 | 13,14 | 12,14 | 13 |
| FGA | 23 | 23 | 23 | 19,23.2 | 22,23 |
| D10S1248 | 13,17 | 13,17 | 13,17 | 14,15 | 15,17 |
| D22S1045 | 11,15 | 15 | 11,15 | 17 | 11,15 |
| D1S1656 | 15,16,17 | 16,17 | 15,17 | 16 | 15 |
| D13S317 | 8,9,11 | 8,9 | 9,11 | 9,11 | 8,11 |
| D7S820 | 8,11 | 11 | 8,11 | 8,11 | 8,11 |
| Penta E | 14,15,21 | 14,15 | 15,21 | 11,14 | 13,21 |
| Penta D | 9,11,13 | 9,11 | 11,13 | 12,13 | 12,13 |
| TH01 | 7,9 | 7,9 | 9 | 6 | 7,9 |
| D12S391 | 17,19,24 | 19,24 | 17,24 | 19 | 17,18 |
| D2S1338 | 21,23,25 | 21,23 | 21,25 | 18,19 | 20,25 |
| TPOX | 8,11 | 8,11 | 8 | 8,9 | 8 |
| Amelogenin | X,Y | X | X,Y | X,Y | X,Y |
| 基因座 | 待测个体基因型 | HP | HD | LR |
|---|---|---|---|---|
| D3S1358 | 16 | 0.100 | 2.931×10-2 | 3.419 |
| vWA | 15 | 2.940×10-2 | 1.326×10-3 | 22.175 |
| D16S539 | 9,12 | 9.022×10-2 | 1.645×10-2 | 5.485 |
| CSF1PO | 8,13 | 2.602×10-2 | 5.932×10-4 | 43.872 |
| D6S1043 | 12,14 | 3.508×10-2 | 1.735×10-3 | 20.218 |
| D8S1179 | 10,12 | 3.778×10-2 | 2.038×10-3 | 18.540 |
| D21S11 | 30,31.2 | 9.637×10-2 | 5.343×10-3 | 18.035 |
| D18S51 | 13,16 | 3.264×10-2 | 4.881×10-3 | 6.688 |
| D5S818 | 9,12 | 1.689×10-2 | 1.537×10-3 | 10.995 |
| D2S441 | 11,14 | 1.050×10-2 | 1.141×10-3 | 9.202 |
| D19S433 | 13,14 | 8.238×10-2 | 2.540×10-2 | 3.244 |
| FGA | 23 | 8.600×10-2 | 1.114×10-2 | 7.718 |
| D10S1248 | 13,17 | 1.804×10-2 | 2.983×10-3 | 6.048 |
| D22S1045 | 11,15 | 0.101 | 1.403×10-2 | 7.232 |
| D1S1656 | 15,17 | 3.384×10-2 | 3.629×10-3 | 9.325 |
| D13S317 | 9,11 | 5.796×10-2 | 7.595×10-3 | 7.631 |
| D7S820 | 8,11 | 0.139 | 1.566×10-2 | 8.857 |
| Penta E | 15,21 | 1.410×10-2 | 2.257×10-4 | 62.475 |
| Penta D | 11,13 | 7.284×10-2 | 5.701×10-3 | 12.778 |
| TH01 | 9 | 0.207 | 8.910×10-2 | 2.320 |
| D12S391 | 17,24 | 1.960×10-2 | 4.225×10-4 | 46.390 |
| D2S1338 | 21,25 | 2.124×10-2 | 3.726×10-4 | 57.017 |
| TPOX | 8 | 0.165 | 0.106 | 1.553 |
Tab. 2 Analysis results of the SMART Mixed DNA Profile Intelligent Analysis System
| 基因座 | 待测个体基因型 | HP | HD | LR |
|---|---|---|---|---|
| D3S1358 | 16 | 0.100 | 2.931×10-2 | 3.419 |
| vWA | 15 | 2.940×10-2 | 1.326×10-3 | 22.175 |
| D16S539 | 9,12 | 9.022×10-2 | 1.645×10-2 | 5.485 |
| CSF1PO | 8,13 | 2.602×10-2 | 5.932×10-4 | 43.872 |
| D6S1043 | 12,14 | 3.508×10-2 | 1.735×10-3 | 20.218 |
| D8S1179 | 10,12 | 3.778×10-2 | 2.038×10-3 | 18.540 |
| D21S11 | 30,31.2 | 9.637×10-2 | 5.343×10-3 | 18.035 |
| D18S51 | 13,16 | 3.264×10-2 | 4.881×10-3 | 6.688 |
| D5S818 | 9,12 | 1.689×10-2 | 1.537×10-3 | 10.995 |
| D2S441 | 11,14 | 1.050×10-2 | 1.141×10-3 | 9.202 |
| D19S433 | 13,14 | 8.238×10-2 | 2.540×10-2 | 3.244 |
| FGA | 23 | 8.600×10-2 | 1.114×10-2 | 7.718 |
| D10S1248 | 13,17 | 1.804×10-2 | 2.983×10-3 | 6.048 |
| D22S1045 | 11,15 | 0.101 | 1.403×10-2 | 7.232 |
| D1S1656 | 15,17 | 3.384×10-2 | 3.629×10-3 | 9.325 |
| D13S317 | 9,11 | 5.796×10-2 | 7.595×10-3 | 7.631 |
| D7S820 | 8,11 | 0.139 | 1.566×10-2 | 8.857 |
| Penta E | 15,21 | 1.410×10-2 | 2.257×10-4 | 62.475 |
| Penta D | 11,13 | 7.284×10-2 | 5.701×10-3 | 12.778 |
| TH01 | 9 | 0.207 | 8.910×10-2 | 2.320 |
| D12S391 | 17,24 | 1.960×10-2 | 4.225×10-4 | 46.390 |
| D2S1338 | 21,25 | 2.124×10-2 | 3.726×10-4 | 57.017 |
| TPOX | 8 | 0.165 | 0.106 | 1.553 |
| [1] | 林锦锋,胡森杰. 利用Y-STR家系排查外来暂住人口破获杀人案1例[J].法医学杂志,2017,33(3):335-336. doi:10.3969/j.issn.1004-5619.2017.03.035 . |
| LIN J F, HU S J. A homicide case solved by Y-STR pedigree investigation of non-native population[J]. Fa-yixue Zazhi,2017,33(3):335-336. | |
| [2] | 张斌. Y-STR数据库在案件侦查中的应用2例[J].法医学杂志,2013,29(6):489. doi:10.3969/j.issn.1004-5619.2013.06.032 . |
| ZHANG B. Application of Y-STR databases in criminal investigation: Two case reports[J]. Fayixue Zazhi,2013,29(6):489. | |
| [3] | BUTLER J M. 法医DNA分型专论:证据解释[M].侯一平,李成涛,严江伟,译. 北京:科学出版社,2018:102-136. |
| BUTLER J M. Advanced topics in forensic DNA typing: Interpretation[M]. HOU Y P, LI C T, YAN J W, transl. Beijing: Science Press,2018:102-136. | |
| [4] | 余华光,曹禹. 弃婴案中混合斑DNA分型拆分1例[J].法医学杂志,2022,38(3):339-341. doi:10.12116/j.issn.1004-5619.2021.510906 . |
| YU H G, CAO Y. Resolution of mixed spot DNA genotyping in the discard infant: A case report[J]. Fayixue Zazhi,2022,38(3):339-341. | |
| [5] | 李甫,徐磊,蔺晨,等. 两种混合STR分型分析软件的比较与应用[J].刑事技术,2022,47(1):18-23. doi:10.16467/j.1008-3650.2021.0162 . |
| LI F, XU L, LIN C, et al. Comparison and application of two pieces of software for interpretation of mixed STR profiles[J]. Xingshi Jishu,2022,47(1):18-23. | |
| [6] | 彭柱,徐珍,凃政,等. 混合STR分型分析方法研究进展[J].刑事技术,2022,47(1):10-17. doi:10.16467/j.1008-3650.2021.0114 . |
| PENG Z, XU Z, TU Z, et al. Evolving researches into mixed STR profiles for their analysis[J]. Xingshi Jishu,2022,47(1):10-17. | |
| [7] | 吕铷麟. 现场混合生物物证的DIP-STR鉴定体系构建及应用研究[D].北京:中国人民公安大学,2023. |
| LÜ R L. Construction and application study of DIP-STR identification system for on-site mixed biological evidence[D]. Beijing: People’s Public Security University of China,2023. | |
| [8] | 吴玉剑,方慧,刘翠兰,等. 运用二代测序技术拆分混合STR分型[J].刑事技术,2021,46(1):104-107. doi:10.16467/j.1008-3650.2021.0020 . |
| WU Y J, FANG H, LIU C L, et al. Separation of mixed STR profiles through next generation sequencing: Case report[J]. Xingshi Jishu,2021,46(1):104-107. | |
| [9] | 齐涛,王世嘉. 强奸致孕案件40天完整孕囊DNA检验成功讨论[C]//公安部鉴定中心. 2022法医遗传学新进展.北京:群众出版社,2023:321-322. |
| QI T, WANG S J. Discussion on the successful DNA testing of an intact gestational sac within 40 days in a rape-induced pregnancy case[C]// Institute of Forensic Science of China. 2022 new advances in forensic genetics. Beijing: Qunzhong Publishing House,2023:321-322. |
| [1] | Le YANG, He REN, Yan SHI, Chong CHEN, Li JIA, Qian YANG, Yacheng LIU, Jiangwei YAN. Empirical Classification of Tri-Allelic Genotype Cases and Parentage Index Calculation [J]. Journal of Forensic Medicine, 2026, 42(3): 254-260. |
| [2] | Guohua SHU. Practice and Prospect of Forensic Medicine Technology Transfer Under Policy Empowerment [J]. Journal of Forensic Medicine, 2026, 42(3): 191-195. |
| [3] | Xiaodan HE. Current Status Analysis and Pathway Exploration of the Technology Transfer in Forensic Medicine [J]. Journal of Forensic Medicine, 2026, 42(3): 196-206. |
| [4] | Qunyan LIU, Jinming YANG, Xiaoyu GUO. Strategies for Constructing a Technology Transfer System in Forensic Medicine Based on National Policies and Disciplinary Characteristics [J]. Journal of Forensic Medicine, 2026, 42(3): 207-214. |
| [5] | Jichao XU, Xiaohui CHEN, Qin SU, Dang’en GU, Tianchun LIN, Jianmiao ZHANG, Liang HAN, Ming CAI, Jian ZHAO, Quyi XU. Rapid Detection of Planktonic Microorganism DNA in Drowning: Technology Transfer and Application Implications [J]. Journal of Forensic Medicine, 2026, 42(3): 215-219. |
| [6] | Jiemin CHEN. Strategies and Pathways for Transferring Visual Evoked Potential Technology into Forensic Clinical Identification [J]. Journal of Forensic Medicine, 2026, 42(3): 220-223. |
| [7] | Yunfeng ZHANG, Xinwei LIU, Linpei DONG, Xiaojun WU, Peng ZHAO, Jing RAN. Application of Portable Mass Spectrometry System in On-site Rapid Detection [J]. Journal of Forensic Medicine, 2026, 42(3): 224-231. |
| [8] | Lei TANG, Weihong XIE, Chengfei ZHUO, Chen XU, Huanhuan YAO, Xiaofei LI, Jianwei ZHANG, Yang LI, Jianbo YING. Development of a Fully Automated Blood Alcohol Analyzer and Its Application in Forensic Science [J]. Journal of Forensic Medicine, 2026, 42(3): 232-239. |
| [9] | Yawen XIAO, Yaoran YANG, Chongjun YANG, Yan SUN, Yue CHEN, Naihan HAN, Yuan MENG, Wenjun WANG, Qingshui REN, Jing ZHU, Tongshu ZHANG, Bing WANG, Liyan ZHANG. Application of Automatic Magnetic Solid-Phase Extraction Instrument in Toxic Substances and Illegal Drugs [J]. Journal of Forensic Medicine, 2026, 42(3): 240-246. |
| [10] | Jianghuan LU, Yixin MA, Zhiao DUAN, Xiaoshi QIN, Yunchao ZHOU, Jianhua CHEN, Jianqiang DENG. Application of Multi-Organ Synchronous Continuous Temperature Monitoring in the Analysis of Postmortem Temperature Changes [J]. Journal of Forensic Medicine, 2026, 42(3): 247-253. |
| [11] | Mingjin YANG, Meiyun HE, Weian DU, Pengfei MEI, Xuelian CHENG, Xin LIU, Yuesen SHI, Hao JIN, Yiling HU, Meixin HE, Ling CHEN, Chao LIU. Enzyme Digestion LC-MS/MS Detection of Etomidate, Ketamine, Methamphe‑ tamine and Codeine in Hair [J]. Journal of Forensic Medicine, 2026, 42(3): 261-268. |
| [12] | Zheng QIAO, Hui YAN, Hang CHEN. Illegal Drug: Metonitazene [J]. Journal of Forensic Medicine, 2026, 42(3): 269-272. |
| [13] | Xiaotian YU. Common Problems and Recommendations for Manuscripts Submitted to Fayixue Zazhi [J]. Journal of Forensic Medicine, 2026, 42(3): 273-280. |
| [14] | Xinyang LIU, Yazhen CHEN, Yumeng SUN, Ze WU, Jiayi XU, Rubo LI, Xu WU, Libala HU, Pengfei WANG, Minghui ZHAO, Rui ZHAO. Heat Stroke Caused by Folk Remedy of “Tiaochoufan”: A Case Report [J]. Journal of Forensic Medicine, 2026, 42(3): 285-287. |
| [15] | Xiangtao MA, Yi WU, Wendong MAO, Congda SHEN, Zewei YAO, Lijie YE, Rui ZHU, Yiwu ZHOU. Fatal Adhesive Tape Wrapping Around the Mouth and Nose: Two Case Reports [J]. Journal of Forensic Medicine, 2026, 42(3): 288-291. |
| Viewed | ||||||
|
Full text |
|
|||||
|
Abstract |
|
|||||