Gas chromatography with dual nitrogen-phosphorus detection and flame ionization detection for screening abuse drugs

Abstract

Abstract: A dual-detection Gas chromatographic method for screening out abuse drugs is described A single capillary separation column is connected to a nitrogen-phosphorus detection (NPD) and a flame ionization detection (FID) by an Y-connector The ratio responded by NPD/FID is influenced by operational conditions But the relative ratio is not influenced when carbetane is used as a reference The ratio and the relative ratio can be used to screening abuse drugs

Key words: GC, screen, abuse drugs, NPD, FID

SUN YAJUAN;ET AL (INSTITUTE OF FORENSIC SCIENCES;MINISTRY OF JUSTICE;SHANGHAI 000;P R CHINA). Gas chromatography with dual nitrogen-phosphorus detection and flame ionization detection for screening abuse drugs[J]. , 2000, 16(2): 81-83+1.

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[14]	QIANG HUO-SHENG, CHEN HANG, SHEN BAO-HUA,ET AL.. Determination of Sulfide Ion in Blood from Hydrogen Sulfide Poisoning Cases [J]. , 2017, 33(2): 148-153.
[15]	CEN XIN-HAI, ZHANG ZHI-XIANG, WANG TAO, ET AL.. The Role of Hydrogen Sulfide in Acute Liver Injury Induced by Traumatic Stress in Rats [J]. , 2016, 32(2): 81-85.

Gas chromatography with dual nitrogen-phosphorus detection and flame ionization detection for screening abuse drugs

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