Cell apoptosis in closed cerebellar contusion in rat

Abstract

Abstract: Objective To observe the cell apoptosis explore closed cerebellar contusion in rat.Methods SD rats model of contusion was established and apototic cells were detected by TUNEL method at5,10,30,45,60min and2,4,6,8,12h,after injury.Results apototic cells in contusion area appeared at1h after closed cerebellar contusion,reached the peak at4-6h,then decreased and so as marginal area where the peak was in6-8h.Conclusion The apoptotic index of closed contusion of cerebellum in different injury time may provide a new sensitive and objective method for the forensic early injury time estimation.

Key words: closed cerebellar, contusion, apoptosis, injury time estimation

LI XING-BIAO;HU YUN;XIA KANG(DEPARTMENT OF PATHOLOGY;WENZHOU MEDICAL COLLEGE;WENZHOU;ZHEJIANG0). Cell apoptosis in closed cerebellar contusion in rat[J]. , 2002, 0(2): 74-75+7.

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Cell apoptosis in closed cerebellar contusion in rat

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