Journal of Forensic Medicine ›› 2026, Vol. 42 ›› Issue (1): 66-68.DOI: 10.12116/j.issn.1004-5619.2026.360302

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Synthetic Drug: Pregabalin

Hang CHEN(), Xin WANG, Hui YAN, Ping XIANG()   

  1. Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China
  • Received:2026-01-04 Online:2026-04-28 Published:2026-02-25
  • Contact: Ping XIANG

Abstract:

Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid. Currently, the number of deaths related to the misuse or abuse of pregabalin is gradually increa-sing, and there is an urgent need for relevant forensic toxicological information. Based on relevant do-mestic and international research, this article systematically reviews the pharmacological effects, toxicity data, poisoning symptoms, in vivo processes of pregabalin, as well as the toxicological data of various existing typical cases, with the aim of providing a reference for forensic identification.

Key words: forensic medicine, toxicological analysis, pregabalin, pharmacological effects, symptoms of poisoning, in vivo process

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