法医学杂志 ›› 2004, Vol. 0 ›› Issue (1): 21-22.

• 论文 • 上一篇    下一篇

中国成都汉族群体三个Y-STR基因座复合扩增及其单倍型的研究

贾怡,张林,吴梅筠,周斌   

  1. 四川大学华西基础医学与法医学院,教育部人类疾病生物治疗重点实验室,四川大学华西基础医学与法医学院,四川大学华西基础医学与法医学院 四川成都610041 ,四川成都610041 ,四川成都610041 ,四川成都610041
  • 发布日期:2004-02-25 出版日期:2004-02-28

A population study of three Y-STR loci by multiple xing in Han population in Chengdu,China

JIA YI 1 ,ZHANG LIN 2 ,WU MEI-YUN 1 (1.WEST CHINA PRECLINICAL AND FORENSIC MEDICINE COLLEGE,SICHUAN UNIVERSITY,C HENGDU610041,CHINA;2.KEY LABORATORY OF BIOTHERAPY OF HUMAN DISEASES,MINISTRY OF EDU-CATION,CHENGDU610041,CHINA)[   

  • Online:2004-02-25 Published:2004-02-28

摘要: 目的建立一种同步检测Y-STR基因座的方法。方法采用复合扩增的方法同时对三个基因座(DYS390、DYS391及DYS393)进行扩增。结果成功地对这三个Y-STR基因座进行了同步扩增,并用其对中国成都汉族群体进行群体遗传学研究。结论三个Y-STR基因座在中国成都汉族群体个人识别几率为0.8965±0.0081,证明这个体系可用于个人识别和群体遗传学研究。

关键词: 法科学, Y-STRs, DYS393, DYS391, DYS393, 复合扩增, 单倍型

Abstract: Objective To establish a better met ho d determing three Y-STR loci.Methods A multiplex of Y-STRs and amplify simultane ously three Y-STRs loci.Results Establish successfully a multiplexing sys - tem of three Y-STR loci(DYS390,DYS391and DYS393)followed by a population gen etic study of Han population in Chengdu,China.Conculusion The diversity of haplo type is0.8965,the value of discrimina - tion and the chance of exclusion chance is0.8965with the standard error0.008 1.This established system is one of the good tools in personnal identification a nd genetic study.[

Key words: forensic science, Y-STRs, DYS390, DYS391, DYS393, mu ltiplexing, haplotype