法医学杂志

法医学杂志 ›› 2004, Vol. 0 ›› Issue (3): 164-166.

• 论文 • 上一篇    下一篇

中国东部蒙古族人群15个STR基因座多态性研究

杜庆新,王剑,黄玉立,刘牧,沈淑萍,陈彩,李晓平,顾明波   

  1. 黑龙江省公安厅刑事技术处遗传室,黑龙江省公安厅刑事技术处遗传室,黑龙江省公安厅刑事技术处遗传室,内蒙古科技大学医学院,内蒙古科技大学医学院,内蒙古科技大学医学院,黑龙江省公安厅刑事技术处遗传室,黑龙江省公安厅刑事技术处遗传室 黑龙江哈尔滨150008 ,黑龙江哈尔滨150008 ,黑龙江哈尔滨150008 ,内蒙古包头014010 ,内蒙古包头014010 ,内蒙古包头014010 ,黑龙江哈尔滨150008 ,黑龙江哈尔滨150008
  • 发布日期:2004-06-25 出版日期:2004-06-28

A genetic study of 15 STR loci in Chinese East Mongolian population

DU QING-XIN,WANG JIAN,HUANG YU-LI,ET AL.(CRIMINAL SCIENCE&TECHNOLOGY INSTITUTE OF HEI-LONGJIANG PROVINCE,HARBIN150008,CHINA)   

  • Online:2004-06-25 Published:2004-06-28

被引次数

1

摘要： 目的调查15个STR基因座在中国东部蒙古族人群中的基因频率分布。方法应用四色荧光标记引物复合扩增技术,对105名东部蒙古族无关个的血样15个STR基因座进行多态性研究。结果在东部蒙古族人群中15个STR基因座偶合率在0.0084～0.2169之间,个体识别概率(DP)在0.7831～0.9916之间,杂合度在0.5619～0.9231之间,三联非父排除率(PE)在0.4490～0.8444之间,多态性信息总量(PIC)在0.5438～0.9178之间,15个STR基因座总TDP值为0.9999999999998,所有基因座经χ2检验符合Hard-Weinberg平衡。结论上述15个STR基因座在东部蒙古族人群中等位基因分布较好,个体识别率高,适合法医个体识别和亲子鉴定。

关键词: 法科学, 东部蒙古族, STR基因座, 复合扩增, 遗传多态性

Abstract: Objective To investigate the genetic polymorphisms of15STRs loci in Chinese East Mongo-lian population.Methods DNA samples from105unrelated individuals in Chinese East Mongolian popu-lation were screened by Power Plex16System and ABI3100Genetic Analyzer.Results The genotype fre-quencies of these15STR loci meet the Hardy-Weinberg expectation.The Matching probability of15STRs loci were between0.0084～0.2169,discriminating power(DP)at0.7831～0.9916,heterozygosity(H)at0.5619～0.9231,power of exclusion(PE)at0.4490～0.8444,polymorphism information content(PIC)at0.5438～0.9178.The total DP of15STRs loci is0.9999999999998.Conclusion Our results showed that the15STRs loci of Power Plex16System are valuable STR loci genetic marker system having high DP and are useful in forensic case work in Chinese East Mongolian population.

Key words: forensic science, east mongolian population, STR loci, multiplexing PCR, genetic polymorphism