法医学杂志

法医学杂志 ›› 2006, Vol. 0 ›› Issue (3): 230-232.

• 论文 • 上一篇    下一篇

婴幼儿猝死综合征神经病理学的研究进展

金波;黄瑞润;白鹏;廖志钢;   

  1. 四川大学华西基础医学与法医学院,瑞安市公安局法医室,四川大学华西基础医学与法医学院,四川大学华西基础医学与法医学院 四川成都610041,浙江温州325200,四川成都610041,四川成都610041
  • 发布日期:2006-06-25 出版日期:2006-06-28

The Advances in the Neuropathology of Sudden Infant Death Syndrome

JIN BO1,HUANG RUI-RUN2,BAI PENG1,LIAO ZHI-GANG1(1.WEST CHINA PRECLINIAL AND FORENSIC COLLEGE,SICHUAN UNIVERSITY,CHENGDU 610041,CHINA; 2.BUREAU OF PUBLIC SECURITY OF RUIAN,WENZHOU 325200,CHINA)   

  • Online:2006-06-25 Published:2006-06-28

被引次数

2

摘要： 婴幼儿猝死综合征(SIDS)是指发生于1岁以内婴儿无明显病因的突然死亡,其死亡原因及鉴别诊断标准迄今仍不明确。本文参考了近年来采用免疫组化方法对SIDS神经系统病理变化的研究文献,提出SIDS致命的病理生理机制是与睡眠相关的呼吸循环失控或衰竭,即SIDS的主要病因存在于中枢神经系统,但不是单一病因。

关键词: 婴幼儿猝死综合征, 神经病理学, 免疫组织化学

Abstract: Sudden infant death syndrome is known as sudden death in 12 months postnatal without obvious cause,the cause of death and differential diagnosis of still couldn′t be indefinite so far.In this paper,the recent studies on the SIDS neuropathology using immunohisto- chemical technology were reviewed in order to suggest the lethal patho-physiologic derangement or mechanism in SIDS involves dysfunction of sleep-related cardio-respiratory homeostatic controls or failure to arouse. Thus the main cause of SIDS lies in central nerve system,but not unique cause.

Key words: SIDS, neuropathology, immunohistochemistry