法医学杂志 ›› 2007, Vol. 0 ›› Issue (6): 453-456.

• 论文 • 上一篇    下一篇

癫的神经病理学研究进展

张磊;张洋;范氾;揭娅;朱少华;刘良;周亦武;   

  1. 华中科技大学同济医学院法医学系,长沙市公安局芙蓉区分局刑警大队,华中科技大学同济医学院法医学系,华中科技大学同济医学院法医学系,华中科技大学同济医学院法医学系,华中科技大学同济医学院法医学系,华中科技大学同济医学院法医学系 湖北武汉430030,湖南长沙410000,湖北武汉430030,湖北武汉430030,湖北武汉430030,湖北武汉430030,湖北武汉430030
  • 发布日期:2007-12-25 出版日期:2007-12-28

Recent Progress in Epilepsy in Neuropathology

ZHANG LEI1, ZHANG YANG2, FAN FAN1, JIE YA1, ZHU SHAO-HUA1, LIU LIANG1, ZHOU YI-WU1 (1.DEPARTMENT OF FORENSIC MEDICINE,TONGJI MEDICAL COLLEGE, HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY,WUHAN 430030,CHINA ;2. BUREAU OF PUBLIC SECURITY OF CHANGSHA, CHANG   

  • Online:2007-12-25 Published:2007-12-28

摘要: 癫是一种常见的脑疾病,可引起猝死,以往人们侧重于对癫脑电活动的研究,而近年来癫的神经病理学研究已成为临床和法医工作者的一个研究热点。本文依据一系列文献资料分别从癫的发育障碍、瘤性异常增殖、海马硬化、双重病理改变、苔藓纤维发芽等神经病理学变化方面进行综述,进而探讨其法医学意义,希望对癫猝死的法医病理学诊断提供一定的帮助。

关键词: 法医病理学, 癫, 神经病理学, 海马硬化, 癫猝死

Abstract: Epilepsy is a common cerebral disease, and may cause sudden death. Although electric activity study of epileptic brain had been emphasized in the past, the neuropathological study of epilepsy has become a main focus in clinical and forensic medicine recently. This article reviews the recent progress in neuropathology of epilepsy including developmental disorder, abnormal tumoral proliferation, hippocampal sclerosis, dual pathological alteration, and mossy fiber sprouting. Its significance in forensic medicine, particularly for the diagnosis of sudden unexpected death in epilepsy, is discussed.

Key words: forensic pathology, epilepsy, neuropathology, hippocampal sclerosis, sudden unexpected death in epilepsy