法医学杂志

法医学杂志 ›› 2017, Vol. 33 ›› Issue (4): 397-401.DOI: 10.3969/j.issn.1004-5619.2017.04.014

• 综述 • 上一篇    下一篇

宏基因组学在法医学鉴定中的应用

萨日娜1，蔡令艺2，武会娟1，严江伟3，刘  旭1，胡  荣1   

  1. （1. 北京市理化分析测试中心，北京 100089； 2. 济宁市精神病防治院，山东 济宁 272051； 3. 中国科学院北京基因组研究所，北京 100101）
  • 发布日期:2017-08-25 出版日期:2017-08-28
  • 通讯作者: 武会娟，女，博士，主要从事先进分子生物学技术在司法鉴定中的应用研究；E-mail：whjmmwhj@126.com
  • 作者简介:萨日娜（1987—），女，蒙古族，博士，主要从事宏基因组与法医学相关研究；E-mail：benxiongsrn@126.com

Application of Metagenomics in Forensic Identification

SA RI-NA1, CAI LING-YI2, WU HUI-JUAN1, YAN JIANG-WEI3, LIU XU1, HU RONG1   

  1. （1. Beijing Center for Physical and Chemical Analysis, Beijing 100089, China; 2. Jining Hospital for Prevention and Treatment of Psychiatric Diseases, Jining 272051, China; 3. Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China）
  • Online:2017-08-25 Published:2017-08-28

被引次数

2

摘要： 随着分子生物学与基因组学的发展，宏基因组学在法医学与法医学鉴定中逐渐扮演着重要的角色。近年来，宏基因组学作为研究环境微生物菌群构成与多样性、各成员之间相互关系及与环境之间相互关系的分支学科，在法医学鉴定相关领域的应用也逐渐兴起，并带来了新的契机。本文对宏基因组学研究策略及其在法医学鉴定中个体识别、案发现场生物斑迹来源鉴定及药物滥用检测等方面的应用现状进行了综述，旨在进一步阐明宏基因组学在法医学中的作用与应用价值。

关键词: 法医遗传学, 宏基因组学, 综述, 基因组, 微生物, 个体识别

Abstract: With the development of molecular biology and genomics, metagenomics is playing a more important role in forensic science and forensic identification. In recent years, as a branch discipline studying the composition profile and diversity of microbe flora as well as studying the interaction within microbe and with environment, the application of metagenomics has gradually risen and brought new opportunities for forensic identification-related area. In this review, strategy of metagenomics and its application in forensic identification including individual identification, origin determination of biological stain in crime scene and drug abuse detection are summarized. This article aims to elucidate the role and application value of metagenomics in forensic science.

Key words: forensic genetics, metagenomics, review, genome, microbial, personal identification

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