法医学杂志

法医学杂志 ›› 2019, Vol. 35 ›› Issue (1): 1-4，10.DOI: 10.12116/j.issn.1004-5619.2019.01.001

• 论著 •    下一篇

家兔溺死模型肺CT影像参数的特征性变化及3D虚拟测量

简俊祺1，2， 邓德元3， 万雷2， 邹冬华2， 王卓群1，2， 刘宁国2， 陈忆九2   

  1. 1. 苏州大学医学部法医学系，江苏 苏州 215123； 2. 司法鉴定科学研究院 上海市法医学重点实验室 上海市司法鉴定专业技术服务平台，上海 200063； 3. 上海市公安局水上公安局，上海 200002
  • 发布日期:2019-02-25 出版日期:2019-02-28
  • 通讯作者: 通信作者：刘宁国，男，研究员，主任法医师，主要从事法医病理学研究；E-mail：liuningguo@foxmail.com 通信作者：陈忆九，男，研究员，博士研究生导师，主要从事法医病理学研究；E-mail：chenyj@ssfjd.cn
  • 作者简介:简俊祺（1992—），男，硕士研究生，主要从事法医病理学研究；E-mail：junqijian@163.com
  • 基金资助:
    “十三五”国家重点研发计划资助项目（2016YFC0800702）；上海市法医学重点实验室资助项目（17DZ2273200）；上海市司法鉴定专业技术服务平台资助项目（16DZ2290900）

Characteristic Changes and 3D Virtual Measurement of Lung CT Image Parameters in the Drowning Rabbit Model

JIAN Jun-qi1,2, DENG De-yuan3, WAN Lei2, ZOU Dong-hua2, WANG Zhuo-qun1,2, LIU Ning-guo2, CHEN Yi-jiu2   

  1. 1. Department of Forensic Medicine, Medical College of Soochow University, Suzhou 215123, Jiangsu Pro-vince, China; 2. Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China; 3. Water Public Security Bureau, Shanghai Public Security, Shanghai 200002, China
  • Online:2019-02-25 Published:2019-02-28
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摘要： 目的 应用虚拟解剖技术对比分析实验性家兔溺死模型肺部CT影像的死后特征性改变及3D虚拟模型相关参数的差异，探讨其在法医病理学溺死诊断中的应用价值。 方法 建立家兔溺死模型，并以失血性休克、机械性窒息的动物模型做对照。对实验动物行CT断层扫描，通过断层图像形态学阅片观察比较各组间影像学特征差异。将CT扫描数据导入Mimics 14.0软件进行3D建模，通过软件自动化分析计算出肺部CT值和肺体积，分析不同死亡原因引起的肺部CT值及体积差别。 结果 溺死组肺部CT影像均表现为特征性的弥漫性毛玻璃样改变（弥漫性均匀一致的密度增高影），失血性休克组相应部位未见明显异常，机械性窒息组仅少部分有类似改变。与失血性休克和机械性窒息组相比，溺死组肺部CT值和体积均明显增大（P<0.05）。 结论 在死后肺部影像的基础上，结合肺体积及CT值变化，可有效反映出溺死尸体肺部虚拟解剖特征性改变，为溺死的法医学鉴定提供诊断依据。

 

关键词: 法医病理学；溺水；肺；成像, 三维；虚拟解剖；兔

Abstract: Objective To use virtual anatomy technique in the analysis of post-mortem characteristic changes of CT images in the experimental drowning rabbit model and the related parameters in 3D virtual model, so as to explore its application value in the diagnosis of drowning in forensic pathology. Methods A model of drowning rabbits was established, with animal models of hemorrhagic shock and mechanical asphyxia as the controls. CT scan was performed on the experimental animals, and the differences in imaging features between the groups were compared by morphological reading of the tomographic images. CT data were imported into Mimics 14.0 software for 3D modeling. The CT values and lung volumes were calculated by the software, and the differences on CT values and lung volumes brought by different causes of death were analyzed. Results The CT images of lungs in the drowning group showed characteristic ground-glass opacity （diffuse and uniform density increase）. There were no obvious abnormalities in hemorrhagic shock group, and only a few similar changes were found in the mechanical asphyxia group. Compared with the controls, the CT values and the lung volumes in the drowning group were significantly increased （P<0.05）. Conclusion Based on post-mortem lung imaging, the combination of CT value and lung volume changes can effectively reflect the virtual anatomical features in drowning, and provide a diagnostic basis for the forensic identification of drowning.

Key words: forensic pathology, drowning, lung, imaging, three-dimensional, virtopsy, rabbits

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