法医学杂志

法医学杂志 ›› 2021, Vol. 37 ›› Issue (4): 561-568.DOI: 10.12116/j.issn.1004-5619.2021.310406

• 综述 • 上一篇    下一篇

合成卡西酮类新精神活性物质对动物行为学影响的研究进展

黄志斌1， 蔡娟1， 林泽彬1， 赵子琴1， 李备栩2   

  1. 1. 复旦大学基础医学院法医学系，上海 200032； 2. 上海政法学院警务学院，上海 201701
  • 发布日期:2021-08-25 出版日期:2021-08-28
  • 通讯作者: 李备栩，男，博士，副主任法医师，主要从事法医病理学和法医临床学鉴定和研究；E-mail：libeixu@shupl.edu.cn
  • 作者简介:黄志斌（1990—），男，博士，主要从事法医毒理学和法医病理学鉴定和研究；E-mail：zhibinhuang13@fudan.edu.cn

Research Progress on the Effect of Synthetic Cathinones on Animal Behavior

HUANG Zhi-bin1, CAI Juan1, LIN Ze-bin1, ZHAO Zi-qin1, LI Bei-xu2   

  1. 1. Department of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; 2. School of Policing Studies, Shanghai University of Political Science and Law, Shanghai 201701, China
  • Online:2021-08-25 Published:2021-08-28

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摘要： 合成卡西酮类是一类具有与苯丙胺类毒品类似结构的新精神活性物质，服用后可产生与苯丙胺、可卡因等毒品类似的兴奋作用。近年来，国内外合成卡西酮类的滥用现象日趋严峻，对社会治安与公共健康均造成了严重威胁。本文着重探讨几种常见合成卡西酮类物质，归纳其在动物自主活动实验、药物依赖模型实验中的研究结果，总结其在动物体温调节、学习记忆与焦虑方面的相关实验结论，以期为国内开展相关滥用物质研究提供数据借鉴和方法指导。

关键词: 法医毒理学, 新精神活性物质, 合成卡西酮类, 药物滥用, 动物行为学, 药物依赖, 综述

Abstract: Synthetic cathinones are a class of new psychoactive substances with a structure similar to amphetamine drugs, which can produce excitatory effects similar to drugs such as amphetamine and cocaine after being taken. In recent years, the abuse of synthetic cathinones worldwide has become increasingly serious, posing a serious threat to social security and public health. This article focuses on several common synthetic cathinones, collects their research results in animal autonomous activity experiments and drug dependence model experiments and summarizes their relevant experimental conclusions in animal body temperature regulation, learning and memory, and anxiety, in order to provide data reference and method guidance for the domestic development of related drug research.

Key words: forensic toxicology, new psychoactive substance, synthetic cathinones, drug abuse, animal ethology, drug dependence, review

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