法医学杂志 ›› 2023, Vol. 39 ›› Issue (2): 161-167.DOI: 10.12116/j.issn.1004-5619.2021.511210
收稿日期:
2021-12-29
发布日期:
2023-06-06
出版日期:
2023-04-25
作者简介:
高红艳(1989—),女,硕士研究生,主要从事法医物证学研究;E-mail:1024097921@qq.com
Hong-yan GAO(), Guang-fu LIU, Jian WU, Peng-yu CHEN
Received:
2021-12-29
Online:
2023-06-06
Published:
2023-04-25
摘要:
随着分子生物学的进展,DNA分析技术在法庭科学中得到了广泛应用。非人源DNA分析可以应用于一些特殊案件,在提供侦查线索和审判依据方面具有独特的法医学价值。动物DNA分型在各类非人源DNA相关案件中作用突出,是法医学非人源DNA分析的主要内容。本文就动物DNA分型技术和特点、法医学应用场景中面临的挑战,综述了其发展历史和现状、优势与不足,并展望了其未来的发展。
中图分类号:
高红艳, 刘光甫, 吴建, 陈鹏宇. 动物DNA分型及其在法医学中的研究进展[J]. 法医学杂志, 2023, 39(2): 161-167.
Hong-yan GAO, Guang-fu LIU, Jian WU, Peng-yu CHEN. Animal DNA Typing and Its Research Progress in Forensic Medicine[J]. Journal of Forensic Medicine, 2023, 39(2): 161-167.
1 | MORI C, MATSUMURA S. Current issues for mammalian species identification in forensic science: A review[J]. Int J Legal Med,2021,135(1):3-12. doi:10.1007/s00414-020-02341-w . |
2 | COLOMBO F M, CATTANEO P, BERNARDI C. Selected results of DNA-based species identification on animal foods[J]. J Sci Food Agric,2018,98(6):2437-2439. doi:10.1002/jsfa.8713 . |
3 | BENTLEY D R. Decoding the human genome sequence[J]. Hum Mol Genet,2000,9(16):2353-2358. doi:10.1093/hmg/9.16.2353 . |
4 | OSTRANDER E A, WAYNE R K. The canine genome[J]. Genome Res,2005,15(12):1706-1716. doi:10.1101/gr.3736605 . |
5 | 姚瑞. 基于高通量DNA测序的南麂列岛海洋底栖环节动物多样性分析[D].舟山:浙江海洋大学,2018. |
YAO R. Analysis of marine benthic annelid diversity in Nanji Islands based on high-throughput DNA sequencing[D]. Zhoushan: Zhejiang Ocean University,2018. | |
6 | 张谊,朱砺. 遗传标记的研究进展[J].畜牧兽医杂志,2001,20(3):18-22. doi:10.3969/j.issn.1004-6704.2001.03.007 . |
ZHANG Y, ZHU L. A review on the progress of genetic markers[J]. Xumu Shouyi Zazhi,2001,20(3):18-22. | |
7 | 周峻荔,韦红英,吴华,等. STR遗传标记在广西地区血友病A携带者诊断中的应用[J].中国当代儿科杂志,2012,14(12):951-955. |
ZHOU J L, WEI H Y, WU H, et al. Application of STR genetic marker system in the detection of hemophilia A carriers in Guangxi, China[J]. Zhongguo Dangdai Erke Zazhi,2012,14(12):951-955. | |
8 | LINACRE A, GUSMÃO L, HECHT W, et al. ISFG: Recommendations regarding the use of non-human (animal) DNA in forensic genetic investigations[J]. Forensic Sci Int Genet,2011,5(5):501-505. doi:10.1016/j.fsigen.2010.10.017 . |
9 | 高红艳. 贵州北部四个民族19个X-STR基因座遗传多态性及群体遗传关系分析[D].遵义:遵义医科大学,2020. |
GAO H Y. Genetic polymorphisms and population study of 19 X-STR loci in four ethnic groups, Nor-thern Guizhou[D]. Zunyi: Zunyi Medical University,2020. | |
10 | KANTHASWAMY S, TOM B K, MATTILA A M, et al. Canine population data generated from a multiplex STR kit for use in forensic casework[J]. J Forensic Sci,2009,54(4):829-840. doi:10.1111/j.1556-4029.2009.01080.x |
11 | MENOTTI-RAYMOND M A, DAVID V A, WACH-TER L L, et al. An STR forensic typing system for genetic individualization of domestic cat (Felis catus) samples[J]. J Forensic Sci,2005,50(5):1061-1070. |
12 | SHANG S, ZHANG M, ZHAO Y, et al. Development and validation of a novel 13-plex PCR system for commonly used short tandem repeats in horses (Equus caballus)[J]. Equine Vet J,2019,51(5):688-695. doi:10.1111/evj.13047 . |
13 | XIA X, YAO Y, LI C, et al. Genetic diversity of Chinese cattle revealed by Y-SNP and Y-STR markers[J]. Anim Genet,2019,50(1):64-69. doi:10.1111/age.12742 . |
14 | MEREDITH E P, ADKINS J K, RODZEN J A. UrsaPlex: An STR multiplex for forensic identification of North American black bear (Ursus americanus)[J]. Forensic Sci Int Genet,2020,44:102161. doi:10.1016/j.fsigen.2019.102161 . |
15 | VAN HOPPE M J C, DY M A V, VAN DEN EINDEN M, et al. SkydancerPlex: A novel STR multiplex validated for forensic use in the hen harrier (Circus cyaneus)[J]. Forensic Sci Int Genet,2016,22:100-109. doi:10.1016/j.fsigen.2016.02.003 . |
16 | TOM B K, KOSKINEN M T, DAYTON M, et al. Development of a nomenclature system for a canine STR multiplex reagent kit[J]. J Forensic Sci,2010,55(3):597-604. doi:10.1111/j.1556-4029.2010.01361.x. . |
17 | YOUSEFI S, ABBASSI-DALOII T, KRAAIJEN-BRINK T, et al. A SNP panel for identification of DNA and RNA specimens[J]. BMC Genomics,2018,19(1):90. doi:10.1186/s12864-018-4482-7 . |
18 | VERSCHEURE S, BACKELJAU T, DESMYTER S. Coding region SNP analysis to enhance dog mtDNA discrimination power in forensic casework[J]. Forensic Sci Int Genet,2015,14:86-95. doi:10.1016/j.fsigen. 2014.09.006 . |
19 | TOZAKI T, KIKUCHI M, KAKOI H, et al. Genetic diversity and relationships among native Japanese horse breeds, the Japanese Thoroughbred and horses outside of Japan using genome-wide SNP data[J]. Anim Genet,2019,50(5):449-459. doi:10.1111/age.12819 . |
20 | BA H, JIA B, WANG G, et al. Genome-wide SNP discovery and analysis of genetic diversity in farmed Sika deer (Cervus nippon) in northeast China using double-digest restriction site-associated DNA sequencing[J]. G3 (Bethesda),2017,7(9):3169-3176. doi:10.1534/g3.117.300082 . |
21 | 袁文华. 家犬驯化过程中群体INDEL结构变异的遗传进化特征研究[D].昆明:云南大学,2019. |
YUAN W H. The evolutionary characteristics of INDEL variation during dog domestication revealed by genome-scaledpopulation analysis[D]. Kunming: Yunnan University,2019. | |
22 | 薛蕾. 山羊Indels筛选鉴定及其与生产性状关联分析[D].重庆:西南大学,2018. |
XUE L. Screening the Indel and its association with the productive traits in goats (Capra hircus)[D]. Chongqing: Southwest University,2018. | |
23 | GAO J, SONG X, WU H, et al. Detection of rs665862918 (15-bp indel) of the HIAT1 gene and its strong genetic effects on growth traits in goats[J]. Animals (Basel),2020,10(2):358. doi:10.3390/ani10020358 . |
24 | 蔡继峰. 苍蝇群落演替及mtDNA分子标记的法医学研究[D].成都:四川大学,2005. |
CAI J F. The investigation of constitution and succession of flies community and the study of molecular markers of their mtDNA in the identification of forensically important species[D]. Chengdu: Sichuan University,2005. | |
25 | ANTIL S, ABRAHAM J S, SRIPOORNA S, et al. DNA barcoding, an effective tool for species identification: A review[J]. Mol Biol Rep,2023,50(1):761-775. doi:10.1007/s11033-022-08015-7 . |
26 | COX J P. Bar coding objects with DNA[J]. Analyst,2001,126(5):545-547. doi:10.1039/b101850g . |
27 | 吴建,高红艳,罗丽,等. DNA条形码技术及其在法医学中的应用展望[J].法医学杂志,2020,36(4):559-564. doi:10.12116/j.issn.1004-5619.2020.04.023 . |
WU J, GAO H Y, LUO L, et al. DNA barcode technology and its application prospects in forensic medicine[J]. Fayixue Zazhi,2020,36(4):559-564. | |
28 | KRESS W J, ERICKSON D L. DNA barcodes: Methods and protocols[J]. Methods Mol Biol Clifton N J,2012,858:3-8. |
29 | 陈伟才. 中国宠物行业现状和发展趋势[J].中国洗涤用品工业,2019(8):56-59. |
CHEN W C. Present situation and development trend of pet industry in China[J]. Zhongguo Xidi Yongpin Gongye,2019(8):56-59. | |
30 | 甘雅玲,郭中伟,刘明辉,等. 刑事案件中动物毛发的扫描电镜研究[J].电子显微学报,2003,22(6):489. doi:10.3969/j.issn.1000-6281.2003.06.019 . |
GAN Y L, GUO Z W, LIU M H, et al. Study on animal hairs in forensic cases by SEM[J]. Dianzi Xianwei Xuebao,2003,22(6):489. | |
31 | 王定明,余春,李世军,等. 贵州省狂犬病流行现状与防治对策研究[C]//2012年中国狂犬病年会论文集.北京,2012:154,327. |
WANG D M, YU C, LI S J, et al. Study on the epidemic status and control strategies of rabies in Guizhou Province[C]// Proceedings of the 2012 China Rabies Annual Conference. Beijing,2012:154,327. | |
32 | 陈鹏飞,罗磊. 动物袭击死亡的法医学鉴定[C]//中国法医学会·全国第二十一届法医临床学学术研讨会论文集.贵阳,2018:396-397. |
CHEN P F, LUO L. Forensic identification of the deaths caused by animal attacks[C]// Chinese Forensic Medicine Association · Proceedings of the 21st Forensic Clinical Medicine Symposium. Guiyang,2018:396-397. | |
33 | 陈积敏,胡诚志,杨帆,等. 野生动物及其制品非法贸易治理策略研究[J].林业经济问题,2021,41(2):136-145. doi:10.16832/j.cnki.1005-9709.20200280 . |
CHEN J M, HU C Z, YANG F, et al. Study on the governance strategy of illegal trade in wildlife and its products[J]. Linye Jingji Wenti,2021,41(2):136-145. | |
34 | 陈积敏,骆家林,陈鸿超,等. 从资源保护到国家战略:野生动植物和森林资源犯罪研究综述[J].林业经济,2016,38(11):87-91. doi:10.13843/j.cnki.lyjj.2016.11.016 . |
CHEN J M, LUO J L, CHEN H C, et al. From resources protection to national strategy: A review of wildlife and forest resources crime research[J]. Linye Jingji,2016,38(11):87-91. | |
35 | 倪萍娅,裴黎,戈文东,等. DNA检验技术在野生动物保护中的应用[J].法医学杂志,2011,27(6):451-454,459. doi:10.3969/j.issn.1004-5619.2011.06.014 . |
NI P Y, PEI L, GE W D, et al. Applications of DNA identification technology in protection of wild animals[J]. Fayixue Zazhi,2011,27(6):451-454,459. | |
36 | 钱林东,张自芳,田应华,等. 利用微卫星DNA标记进行黄牛的亲子鉴定[J].云南农业大学学报,2010,25(1):69-74. |
QIAN L D, ZHANG Z F, TIAN Y H, et al. Pa-rentage identification of yellow cattle based on micro-satellite DNA markers[J]. Yunnan Nongye Daxue Xue-bao,2010,25(1):69-74. | |
37 | LUIKART G, BIJU-DUVAL M P, ERTUGRUL O, et al. Power of 22 microsatellite markers in fluorescent multiplexes for parentage testing in goats (Capra hircus)[J]. Anim Genet,1999,30(6):431-438. doi:10.1046/j.1365-2052.1999.00545.x . |
38 | ZHAO X, QIU Q, LI C, et al. Genome-based development of 15 microsatellite markers in fluorescent multiplexes for parentage testing in captive tigers[J]. PeerJ,2020,8:e8939. doi:10.7717/peerj.8939 . |
39 | KAKOI H, KIJIMA-SUDA I, GAWAHARA H, et al. Individual identification of racehorses from urine samples using a 26-plex single-nucleotide polymorphism assay[J]. J Forensic Sci,2013,58(1):21-28. doi:10.1111/j.1556-4029.2012.02291.x . |
40 | LI J J, REN M L, WANG J, et al. Breeding of new Rehmannia glutinosa variety[J]. J Environ Biol,2016,37(5 Spec No):1037-1042. |
41 | MEHRA P, WELLS A D. Variant to gene mapping to discover new targets for immune tolerance[J]. Front Immunol,2021,12:633219. doi:10.3389/fimmu. 2021.633219 . |
42 | VERMEESCH J R, VOET T, DEVRIENDT K. Prenatal and pre-implantation genetic diagnosis[J]. Nat Rev Genet,2016,17(10):643-656. doi:10.1038/nrg.2016.97 . |
43 | ZOU X, WANG Z, HE G, et al. Genetic variation and population structure analysis of Chinese Wuzhong Hui population using 30 Indels[J]. Ann Hum Biol,2020,47(3):300-303. doi:10.1080/03014460.2020.1736627 . |
44 | OKAE H, MATOBA S, NAGASHIMA T, et al. RNA sequencing-based identification of aberrant imprinting in cloned mice[J]. Hum Mol Genet,2014,23(4):992-1001. doi:10.1093/hmg/ddt495 . |
45 | 董桂李. 法医DNA数据库中低质量数据的处理以及分析[J].法制与社会,2021(3):82-83. doi:10.19387/j.cnki.1009-0592.2021.01.218 . |
DONG G L. Processing and analysis of low quality data in forensic DNA database[J]. Fazhi Yu Shehui,2021(3):82-83. | |
46 | CAMACHO-SANCHEZ M, BURRACO P, GOMEZ-MESTRE I, et al. Preservation of RNA and DNA from mammal samples under field conditions[J]. Mol Ecol Resour,2013,13(4):663-673. doi:10.1111/1755- 0998.12108 . |
47 | 石林春,姚辉,谢丽芳,等. 中国动物药材DNA条形码数据库[J].中国中药杂志,2014,39(12):2155-2159. doi:10.4268/cjcmm20141201 . |
SHI L C, YAO H, XIE L F, et al. Integrated DNA barcoding database for identifying Chinese animal medicine[J]. Zhongguo Zhongyao Zazhi,2014,39(12):2155-2159. | |
48 | 赵婉秋,陈黎,沈军达,等. 动物季节性繁殖机制研究进展[J].浙江农业科学,2017,58(1):150-155. doi:10.16178/j.issn.0528-9017.20170148 . |
ZHAO W Q, CHEN L, SHEN J D, et al. Research progress on the mechanism of seasonal breeding in animals[J]. Zhejiang Nongye Kexue,2017,58(1):150-155. | |
49 | 高雅,阎春霞,金天博,等. 中国19个不同地区汉族亚群的分子遗传学关系[J].西安交通大学学报(医学版),2005,26(2):111-114. doi:10.3969/j.issn.1671-8259.2005.02.005 . |
GAO Y, YAN C X, JIN T B, et al. Research on the molecular genetic relationships of Chinese Han subpopulations[J]. Xi’an Jiaotong Daxue Xuebao (Medical sciences),2005,26(2):111-114. | |
50 | 李莉,刘俊宏,朱如心,等. 16个X-STR基因座的连锁不平衡检验和突变率调查[J].法医学杂志,2014,30(6):437-440. doi:10.3969/j.issn.1004-5619.2014.06.12 . |
LI L, LIU J H, ZHU R X, et al. Linkage disequilibrium and mutation rate analysis of sixteen X-STR loci[J]. Fayixue Zazhi,2014,30(6):437-440. | |
51 | 陆惠玲,孙宏钰,欧雪玲,等. 叔侄指数计算方法[J].法医学杂志,2011,27(6):421-424. doi:10.3969/j.issn.1004-5619.2011.06.006 . |
LU H L, SUN H Y, OU X L, et al. Calculation of the avuncular index[J]. Fayixue Zazhi,2011,27(6):421-424. | |
52 | 郭晓媛,孙昌春,薛思瑶,等. 49AISNP:东亚北方三个族群遗传来源推断[J].遗传,2021,43(9):880-889. doi:10.16288/j.yczz.21-073 . |
GUO X Y, SUN C C, XUE S Y, et al. 49AISNP: A study on the ancestry inference of the three ethnic groups in the north of East Asia[J]. Yichuan,2021,43(9):880-889. | |
53 | 郭宏,李丽,杨辰,等. 动物DNA分析在法庭科学中的应用[J].中国司法鉴定,2012(2):69-71. doi:10.3969/j.issn.1671-2072.2012.02.016 . |
GUO H, LI L, YANG C, et al. The application of animal DNA analysis in forensic science[J]. Zhongguo Sifa Jianding,2012(2):69-71. | |
54 | 朱诗禹,徐伟,高宇,等. 基于线粒体COⅡ基因的中国大豆食心虫不同地理种群遗传分化分析[J].昆虫学报,2017,60(4):475-486. doi:10.16380/j.kcxb.2017.04.012 . |
ZHU S Y, XU W, GAO Y, et al. Analysis of the genetic differentiation among geographic populations of Leguminivora glycinivorella (Lepidoptera: Olethreutidae) in China based on mitochondrial COⅡ gene sequences[J]. Kunchong Xuebao,2017,60(4):475-486. | |
55 | 郑向忠,徐宏发,陆厚基. 动物种群遗传异质性研究进展[J].生物多样性,1997,5(3):210-216. |
ZHENG X Z, XU H F, LU H J. Research progress on population genetic heterogeneity[J]. Shengwu Duoyangxing,1997,5(3):210-216. |
[1] | 刘晋廷, 周莉英, 相佳宏, 李子怡, 谢婉婷, 贠克明, 施妍. 哌嗪类新精神活性物质体内检测研究进展[J]. 法医学杂志, 2024, 40(3): 276-283. |
[2] | 方伟, 郑吉龙, 付奕铭, 刘轶. 利用犬类嗅觉搜索人体遗骸研究进展[J]. 法医学杂志, 2024, 40(3): 269-275. |
[3] | 施蕾, 薛冶, 邱丽蓉, 鲁婷, 范飞, 周宇驰, 邓振华. 基于磁共振成像技术的牙龄推断研究进展[J]. 法医学杂志, 2024, 40(2): 112-117. |
[4] | 李丹阳, 潘宇, 周慧明, 万雷, 李成涛, 汪茂文, 王亚辉. 医学统计和机器学习方法在活体年龄推断中的应用[J]. 法医学杂志, 2024, 40(2): 118-127. |
[5] | 陈云霞, 徐杰, 薛晓明, 李忠杰, 戴玉阳. 赤小豆残叶DNA鉴定重建命案现场1例[J]. 法医学杂志, 2024, 40(2): 216-218. |
[6] | 姚彦汝, 金静, 王英杰, 张金专, 李英哲, 徐永新. 火场生物物证识别研究进展[J]. 法医学杂志, 2024, 40(1): 64-69. |
[7] | 范庆炜, 李凌, 杨慧凌, 邓婷婷, 徐冬冬, 王韵, 杜冰, 严江伟. 法医学混合斑研究现状及趋势的文献计量和可视化分析[J]. 法医学杂志, 2024, 40(1): 20-29. |
[8] | 胡文静, 杨婷婷, 王雅雅, 严江伟. 游离DNA最新研究进展及法医学应用展望[J]. 法医学杂志, 2024, 40(1): 70-76. |
[9] | 邢运虹, 李洋, 王文政, 王亮亮, 孙乐乐, 杜秋香, 曹洁, 何光龙, 孙俊红. 不稳定冠状动脉粥样斑块病理特征及分类[J]. 法医学杂志, 2024, 40(1): 59-63. |
[10] | 刘光渊. 应用多种遗传标记分析同母异父双胞胎亲子鉴定1例[J]. 法医学杂志, 2024, 40(1): 106-108. |
[11] | 云鹏, 陈安琪, 陈丽琴, 李成涛. 42个微单倍型复合检测体系的构建及法医学应用[J]. 法医学杂志, 2024, 40(1): 50-58. |
[12] | 杨彬, 徐璐瑶, 李灵玥, 乔东访, 杜思昊, 岳霞, 王慧君. 全球新型冠状病毒感染(COVID-19)相关死亡的病理变化及死因分析[J]. 法医学杂志, 2023, 39(6): 586-595. |
[13] | 黄逸航, 梁伟波, 蹇慧, 屈胜秋. 基于DNA甲基化推断年龄的建模方法与影响因素[J]. 法医学杂志, 2023, 39(6): 601-607. |
[14] | 高林林, 谢炜, 朱素娟, 李达, 王琴, 洪亮, 李佑英. IDentifier DNA分型盒(炎黄34)的法医学验证及应用评估[J]. 法医学杂志, 2023, 39(6): 579-585. |
[15] | 马星宇, 程浩, 张忠铎, 李烨铭, 赵东. 代谢组学技术结合机器学习算法在损伤时间推断中的研究进展[J]. 法医学杂志, 2023, 39(6): 596-600. |
阅读次数 | ||||||
全文 |
|
|||||
摘要 |
|
|||||